par-4 gene 202
paracaspases 88–5
Parkinson’s disease 202
PEA-15 81
PELLE 80, 87
PERK 99, 117
permeability transition pores (PTP) 54, 108,
121, 131, 137
flickering 109
PERP 207
PFAM 73
plasma membrane blebbing 3
Podospora 94
Porifera, cell death in 151, 155–50
presenilins 115–12
procaspase-7 34
procaspase-8L 114
procaspase-9/Apaf-1/cytochrome c complex
(apoptosome) 6
prohibitin 159
PROSITE 73
protein kinase C (PKC) 11–12
pyrin domain (PYD) (PAAD, DAPIN) 69,
84–2, 86
pyrrolidine dithiocarbamate (PDTC) 202
D-pyrroline-5-carboxylate (P5C)
dehydrogenase 148
RAIDD 29, 82, 94
receptor-interacting protein (RIP) 11, 15, 78
receptor pathway 123, 124
RelB 15
reticulon family 115
Rgl1p 97
rheostat model of dimerization 49–9
RING finger 12
RIP2/RICK 83
rpr 43
RTN-xs 115
Saccharomyces cerevisiae 140
aging in 147
bax in 141
rad 17 174
Vpr in 149
Saccharomyces pombe 141
bak in 141
CED-4 expression in 143
rad9 in 144
Vpr in 149
SAGE (serial analysis of gene expression) 202
Salmonella typhimurium 172–7
Schizosaccharomyces pombe, rad1 in 174
Schrumpfzellen 154
SEK1 (MKK4) 8
sequence profile method 73
serine proteases 219–11
silencer of death domains (SODD) 10
SMAC/DIABLO 6, 7, 41, 89, 138
sequestration of 12–14
SMART 73
stauroporin 109
Suberites domuncula 155
survivin 41TACI 77
tcBid 129, 130
technical knockout 203
Tetrahymena 150, 157–2
Tetrahymena proliferation-activating factor
(TPAF) 158
thapsigargin (TG) 64, 100, 101, 104, 109
thioredoxin 203
TIAF1 206
TNF family 74–2, 75, 221
TNF homology domain (THD) 75
TNF-a 21, 29
TNH 69
TOLL family (TLR, TOLL-like receptors)
80, 86
TOLL/IL-1R domain (TIR) proteins 69, 86–
3, 88
TRACK 159
TRADD (TNFR1-associated DD protein) 4,
15, 78, 80
TRAF domains 69
TRAF-1 12–14, 16
TRAF-2 11, 12–14, 15, 16, 17
TRAF-12 102
TRAIL (Apo-2) 1, 4, 8, 25–5, 26–7, 29–9,
75, 221–12
TRAIL-Rl (DR4) 1, 4, 30
TRAIL-R2 (DR5, Apo2, TRICK2,
KILLER) 2, 4, 26, 29, 30, 31INDEX 311