Self And The Phenomenon Of Life: A Biologist Examines Life From Molecules To Humanity

(Sean Pound) #1

76 Self and the Phenomenon of Life


b2726 Self and the Phenomenon of Life: A Biologist Examines Life from Molecules to Humanity “9x6”


  1. In a letter to Wallich in 1882, Darwin wrote: “I had intentionally left the
    question of the Origin of Life uncanvassed as being altogether ultra vires in
    the present state of our knowledge, and that I dealt only with the manner of
    succession.” See: de Beer G. (1959) Some Unpublished Letters of Charles
    Darwin. Notes Rec. R. Soc. Lond., 14: 12–66.

  2. Richards Dawkins, for one, seemed to entertain this possibility in his book:
    “The present lack of a definitely acceptable account of the origin of life
    should certainly not be taken as a stumbling block for the whole Darwinian
    world view.” See: Dawkins R. (1986) The Blind Watchmaker. Norton,
    New York, (1996 paperback ed. p. 166).

  3. In an article published in the Wall Street Journal (September 12, 2009),
    Dawkins put it more bluntly, “Evolution is the creator of life.”

  4. Cited by Dawkins in his book. See: Dawkins R. (1986) The Blind Watch-
    maker. Norton, New York, (1996 paperback ed. p. 131).

  5. Spiegelman S. (1967) An in vitro analysis of a replicating molecule. Am Sci-
    entist 55: 63–68; Mills DR, Peterson RI, Spiegelman S. (1967) An extracel-
    lular Darwinian experiment with a self-duplicating nucleic acid molecule.
    Proc Natl Acad Sci USA 58: 217–224; Kacian DL, Mills DR, Kramer FR,
    Spiegelman S. (1972) A replicating RNA molecule suitable for a detailed
    analysis of extracellular evolution and replication. Proc Natl Acad Sci USA
    69: 3038–3042.

  6. Darwin C. (1859) The Origin of Species. last sentence.

  7. Dawkins R. (1976) The Selfish Gene. Oxford Univ. Press, Oxford; 1989
    edition.

  8. Dawkins R. (1982) The Extended Phenotype: The Gene as the Unit of
    Selection. Oxford: Freeman, p. 114.

  9. Small segments of RNA can regulate gene expression by acting either
    directly on DNA or indirectly on messenger RNA.

  10. Jablonka E, Lamb MJ. (2005) Evolution in Four Dimensions. MIT Press,
    Cambridge, MA.

  11. Wickner RB. (1994) URE3 as an altered URE2 protein: evidence for a
    prion analog in Saccharomyces cerevisiae. Science 264: 566–569; Sond-
    heimer N, Lindquist S. (2000) Rnq1: an epigenetic modifier of protein
    function in yeast. Molecular Cell 5: 163–172; Li RM, Lindquist S. (2000)
    Creating a protein-based element of inheritance. Science 287: 661–664.

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