70 Khaled A. Selim, Mohamed M. S. Nagia and Dina E. El. Ghwas
Figure 7. Chemical structures (44-59) show the diversity of steroidal metabolites
isolated from endophytic fungi.
Another four merterpenoids compounds were identified from the extracts
of Guignardia mangiferae isolated from the medicinal plant Smilax glabra,
namely guignardones P-S (66-69) (Sun et al., 2015). All the compounds were
screened for cytotoxic activities against various cell lines. Recently in 2016
four meroterpenoids, designated chermesins A-D (70-73) whose crystal
structure was assigned to have drimane-type sesquiterpene nucleus with an
unusual cyclohexa-2,5-dienone unit were firstly reported from the extracts of
the broth of Penicillium chermesinum EN- 480 isolated from the marine red
alga Pterocladiella tenuis (Liu et al., 2016).