358 Chapter 11
- If a person has a 50% reduction in insulin sensitivity, what
happens to insulin release for the person to remain in the
normal curve? - If a person has a 50% increase in insulin sensitivity, what
happens to insulin release for the person to remain in the
normal curve? - A person has impaired glucose tolerance despite having an
insulin secretion 50% greater than normal. What range of
values must be true of the person’s insulin sensitivity? - A person has impaired glucose tolerance despite having an
insulin sensitivity 50% greater than average. What range of
values must be true of the person’s insulin release?
Test Your Quantitative Ability
In the graph below, insulin sensitivity is plotted on the x -axis
and insulin release on the y -axis, using arbitrary units where
1.0 represents average normal values for each measurement.
Individuals with points anywhere in the curved graph line
within the green area are considered normal. IGT 5 impaired
glucose tolerance, indicated by the yellow area of the graph;
T2DM 5 type 2 diabetes mellitus, indicated by the red area of
the graph.
2.0
1.0
0
0 0.5 1.0 1.5 2.0 2.5
Insulin sensitivity
0.5 IGT
T2DM
Normal
Insulin release
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