752 Chapter 20
- Androgens, primarily DHEAS, secreted by the fetal
adrenal cortex are converted into estrogen by the
placenta. - Estrogen secreted by the placenta induces oxytocin
synthesis, enhances uterine sensitivity to oxytocin, and
promotes prostaglandin synthesis in the uterus. These
events culminate in labor and delivery.
E. The high levels of estrogen during pregnancy, acting
synergistically with other hormones, stimulate growth and
development of the mammary glands.
1. Prolactin (and the prolactin-like effects of hCS) can
stimulate the production of milk proteins. Prolactin
secretion and action, however, are blocked during
pregnancy by the high levels of estrogen secreted by the
placenta.
2. After delivery, when estrogen levels fall, prolactin
stimulates milk production.
3. The milk-ejection reflex is a neuroendocrine reflex. The
stimulus of suckling causes reflex secretion of oxytocin.
This stimulates contractions of the lactiferous ducts and
the ejection of milk from the nipple.
Test Your Knowledge
Match these:
- Menstrual phase
- Follicular phase
- Luteal phase
- Ovulation
- A person with the genotype XO has
a. ovaries. c. both ovaries and testes.
b. testes. d. neither ovaries nor testes.
- An embryo with the genotype XX develops female
accessory sex organs because of
a. androgens. c. lack of androgens.
b. estrogens. d. lack of estrogens. - In the male,
a. FSH is not secreted by the pituitary.
b. FSH receptors are located in the Leydig cells.
c. FSH receptors are located in the spermatogonia.
d. FSH receptors are located in the Sertoli cells.
- The secretion of FSH in a male is inhibited by negative
feedback effects of
a. inhibin secreted from the tubules.
b. inhibin secreted from the Leydig cells.
c. testosterone secreted from the tubules.
d. testosterone secreted from the Leydig cells. - Which of these statements is true?
a. Sperm are not motile until they pass through the
epididymis.
b. Sperm require capacitation in the female reproductive
tract before they can fertilize an ovum.
c. A secondary oocyte does not complete meiotic division
until it has been fertilized.
d. All of these are true.
a. High estrogen and
progesterone; low FSH and
LH
b. Low estrogen and
progesterone
c. LH surge
d. Increasing estrogen; low LH
and low progesterone
REVIEW ACTIVITIES
- The corpus luteum is maintained for the first 10 weeks of
pregnancy by
a. hCG. c. estrogen.
b. LH. d. progesterone. - Fertilization normally occurs in
a. the ovaries.
b. the uterine tubes.
c. the uterus.
d. the vagina. - The placenta is formed from
a. the fetal chorion frondosum.
b. the maternal decidua basalis.
c. both a and b.
d. neither a nor b. - Uterine contractions are stimulated by
a. oxytocin. d. both a and b.
b. prostaglandins. e. both b and c.
c. prolactin. - Contraction of the mammary glands and ducts during the
milk-ejection reflex is stimulated by
a. prolactin. c. estrogen.
b. oxytocin. d. progesterone. - If GnRH were secreted in large amounts and at a constant
rate rather than in a pulsatile fashion, which of these
statements would be true?
a. LH secretion will increase at first and then decrease.
b. LH secretion will increase indefinitely.
c. Testosterone secretion in a male will be continuously high.
d. Estradiol secretion in a woman will be continuously high. - The contents of the birth control pill
a. inhibit secretion of gonadotropins.
b. exert negative feedback on the hypothalamus.
c. prevent ovulation.
d. maintain the endometrium.
e. All of these.