AMPK Methods and Protocols

(Rick Simeone) #1

  1. Guigas B, Bertrand L, Taleux N, Foretz M,
    Wiernsperger N, Vertommen D, Andreelli F,
    Viollet B, Hue L (2006) 5-Aminoimidazole-4-
    carboxamide-1-beta-D-ribofuranoside and
    metformin inhibit hepatic glucose phosphory-
    lation by an AMP-activated protein kinase-
    independent effect on glucokinase transloca-
    tion. Diabetes 55(4):865–874

  2. Guigas B, Taleux N, Foretz M, Detaille D,
    Andreelli F, Viollet B, Hue L (2007)
    AMP-activated protein kinase-independent
    inhibition of hepatic mitochondrial oxidative
    phosphorylation by AICA riboside. Biochem J
    404(3):499–507. https://doi.org/10.1042/
    BJ20070105

  3. Kramer DK, Al-Khalili L, Guigas B, Leng Y,
    Garcia-Roves PM, Krook A (2007) Role of
    AMP kinase and PPARdelta in the regulation


of lipid and glucose metabolism in human skel-
etal muscle. J Biol Chem 282
(27):19313–19320. https://doi.org/10.
1074/jbc.M702329200


  1. Stephenne X, Foretz M, Taleux N, van der Zon
    GC, Sokal E, Hue L, Viollet B, Guigas B
    (2011) Metformin activates AMP-activated
    protein kinase in primary human hepatocytes
    by decreasing cellular energy status. Diabetolo-
    gia 54(12):3101–3110. https://doi.org/10.
    1007/s00125-011-2311-5

  2. Taleux N, De Potter I, Deransart C, Lacraz G,
    Favier R, Leverve XM, Hue L, Guigas B (2008)
    Lack of starvation-induced activation of
    AMP-activated protein kinase in the hypothal-
    amus of the Lou/C rats resistant to obesity. Int
    J Obes 32(4):639–647.https://doi.org/10.
    1038/sj.ijo.0803759


Determination of Adenine Nucleotides by HPLC 237
Free download pdf