Fig. 5Mitochondrial respiration analysis in the presence of various energy substrates. Mitochondrial respira-
tion profile of primary neurons in the absence of metabolic substrates (Ctrl) or in the presence of 10 mM
glucose (Glc) (a), 10 mML-lactate (Lac) (d), or in response to the injection of different concentrations of
β-hydroxybutyric acid (1, 5, and 10μMβHBA) (g) or acetoacetate (1, 5, and 10 mM AcAc) (j) as metabolic
300 Claudia Marinangeli et al.