HypothalamusSelective estrogen
receptor modulatorsEstradiolGnRH
GnIHAromatase
inhibitorsAromataseTe stosterone
(serum~500 ng/dl)Te stosterone
(~500 ng/dl)Leydig cellsSertoli cellsFSH Inhibion B
ActivinLHTestesAnterior pituitaryFigure 7.16 Hypothalamic–pituitary–gonadal network. Source: Adapted from http://www.
maleinfertility.org/sites/default/files/styles/panopoly_image_original/public/new_hpg.
jpg?itok=J3X4BcOu and Pinterest: hypothalamic‐pituitary‐adrenal.