Front Matter

(Rick Simeone) #1

22 Introduction to Autism Spectrum Disorders


Hind brain

Hind brain

Mid brain
Mid brain

Mid brain

Mid brain

Fore brain

Fore brain

Spinal cord

Spinal cord

Typical child
Cerebral hemisphere

Cerebral hemisphere

Cerebellum

Cerebellum

Pons

Pons

Medulla

Medulla

25 days

25 days

35 days

35 days

40 days

40 days

50 days

50 days

100 days

100 days

9 months

9 months

5 months

5 months

Autistic child

Figure 1.12 Development of a typical human and an autistic human fetal brain from 25
days to 5 months of gestation. In the majority of autism cases, the problems arise during the
very early stages of the fetal brain development. A few progenitor neurons, destined to
mature into a specialized faculty are killed or mutated, resulting in ASD. An autistic child’s
brain is larger but has parts missing (see text for details). (See insert for color representation of
this figure.)
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