- 1 Introduction to Autism Spectrum Disorders Prologue xiii
- Smell of Autism
- The Roundup™ Conundrum
- Testosterone and Male Gender Bias
- Connecting the Dots
- Why Is There a “Spectrum” in Autism?
- Are Genetic Mutations the Cause of Autism?
- De Novo Mutation ASD Parent and Affected Child Exome Sequencing Display
- More Than 1,000 Genetic and Genomic Disorders and Still Counting
- Certain Brain Compartments? Why Do Certain Chemicals Induce Specific Depletions of
- Genesis of an ASD Brain
- Pinpointing Critical Steps Where the Autistic Brain Emerges
- Is Finding Mutations the Path to Discovering the Genesis of ASD?
- Does Brain Size Matter?
- How Autism Develops in a Fetal Brain
- Why Is There a “Spectrum” in ASD?
- ASD and Vaccines
- Thimerosal Containing Mercury Stays in the Body and Is Very Toxic
- Summary
- References
- 2 What is Autism?
- Legacy of Autism
- A Short History of Autism
- DSM‐5 and the ASD Spectrum
- Changes in ASD diagnosis approved by the APA vi Contents
- Support Practices The impact of the Recent DSM‐5 Changes on Diagnosis and
- A New ASD Diagnosis Category: Social Communication Disorder
- ASD or a Giant Spectrum of Socioneuropsychological Disorders
- Asperger Syndrome
- Pervasive Developmental Disorder Not Otherwise Specified
- Autistic Disorder
- Rett Syndrome
- Childhood Disintegrative Disorder
- Is Autism a Genetic Disease?
- Synthetic Chemicals Lack Coevolutionary Adaptation
- Myth of the Genetic Origin of Autism
- Phenotypic Heterogeneity in Autism
- Be Included in ASD Why Fragile X Syndrome or Tuberous Sclerosis Should Not
- Tuberous Sclerosis
- Is Finding Mutation the Path to Discovering the Origin of ASD?
- How Quickly Does Human DNA Mutate?
- What is the Mutation Rate in the Whole Human Genome?
- Does Brain Size Matter?
- Genetics versus Environment
- References
- 3 Olfaction and Autism
- How Do We Smell?
- Summary and Conclusions
- References
- 4 Oxytocin, Arginine Vasopressin and Autism Spectrum Disorder
- Oxytocin
- Why Oxytocin Therapy May be Important for ASD?
- Oxytocin in ASD Hormones, Neuropeptide Arginine Vasopressin and
- Animals and in Man Development of Oxytocin and AVP Neurons in Various
- Oxytocin and Social Experience in Development
- Oxytocin and Developmental Neurological Disorders
- Exogenous Oxytocin Treatments in Humans
- Intranasal and Intravenous Oxytocin Studies in ASD
- Oxytocin Trials in ASD: Beyond the Hype and Hope
- Summary and Conclusions
- References
- 7 Autism and Exposure to Environmental Chemicals
- Contribution of Fragrances to ASD
- Effects of Fragrances on Male Oxytocin‐Receptor Positive Neurons
- Neurons Effects of Fragrances on Female Oxytocin‐Receptor Positive
- Development How Synthetic Chemicals in Fragrances Affect Fetal Brain
- Synthetic Musks
- How Do Synthetic Musks Get Into the Food Chain?
- How Are People Exposed to Synthetic Musks?
- Musks in Food
- Diethyl Phthalate
- Octinoxate
- Benzyl Benzoate and Benzyl Salicylate
- d‐Limonene
- α‐Pinene
- Synthetic EDCs
- on Our Next Generations? Why Is It Important To Look at EDCs and Their Potential Effects
- Where in Fetal Life Are Androgen Receptors Expressed?
- Why Testosterone is Essential for Engineering a Male Brain
- Spatial Memory
- Anxiety‐Related Behavior
- Play Fighting and Aggression
- Adverse Effects of EDCs and Their Mechanisms of Action
- Effects of Testosterone or AR Mimicking EDCs
- Early Puberty in Males
- Change in Sex Ratio
- Effects of EDCs on Neurodevelopmental and Neuroendocrine Systems
- EDC Effects on Steroid Hormone Receptors in the Brain
- Human Race? Are the EDCs and other Synthetic Chemicals Depopulating the
- Summary
- References
- 8 Maternal Antibodies to Fetal Brain Neurons and Autism
- A Double Jeopardy Link between Damage to the Fetal Brain and Maternal Antibodies:
- Are there Examples of Such an Immune Mechanism?
- Rh Incompatibility
- ABO Incompatibility
- Immune System? Why are Fetal Neuroantigens Immunogenic to the Maternal
- Neurotoxicity, and Autoimmunity? Is There Any Evidence of a Link Between Synthetic Chemicals Exposure,
- The Relationship between Autoimmunity and ASD Contents ix
- The Detection of Fetal Brain Neuroantigens in the Maternal Blood
- the Maternal Antibodies? What are the Functions of the Neuroantigens that are Being Destroyed by
- Animal Models and Neuroantibodies to Autism
- Rhesus Macaques Model
- Studies Using Rodent Models
- Why Do Some Autistic Children Have Bigger Brains?
- of Neurodevelopmental or Neurodegenerative Disorders? Is There a Link between Autoimmunity and Other Forms
- A Chicken and Egg Conundrum
- Disorder Tourette Syndrome and Obsessive Compulsive
- Other Contributing Factors in Neuropsychiatric Disorders
- Infectious Flu Virus
- Influenza Vaccine and Narcolepsy
- Other Viral and Nonviral Infections
- Blood–Brain Barrier
- What is the BBB?
- Summary and Conclusions
- References
- 9 Vaccines and Autism
- Childhood Vaccines and Regressive Autism
- Politics Versus Science in the Vaccination Era
- Using Vaccines A Short Glimpse of the History of Vaccines: Justification for
- What is in the Vaccines?
- Thimerosal
- Pose a Higher Risk of Regressive Autism? What is the Evidence That Organomercurial Vaccines
- A Scientific Narrative Why Thimerosal‐Containing Vaccines are Harmful:
- Age of 3 years? How Much Mercury is Given to Children Before the
- After Vaccination? Why Do Only Small Numbers of Children Develop Regressive Autism
- Who Are at Increased Risk for Regressive ASD? Can Measurements of Abnormal Cytokines Identify Children
- Summary of Contributing Immunological Factors to ASD
- References
- Epilogue
- Index
rick simeone
(Rick Simeone)
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