LWBK1006-24 LWW-Govindan-Review December 12, 2011 19:15
Chapter 24•Cancer of the Breast 335Question 24.22. Compared with the use of adjuvant therapy, the use of neoadjuvant
therapy:
A. Increases the potential for BCS
B. Does not provide an opportunity to test the chemosensitivity of the
tumor
C. Increases OS
D. Decreases the risk of local recurrenceQuestion 24.23. Which of the following statements regarding autologous tissue breast
reconstruction is FALSE?
A. Autologous reconstruction may be performed in patients who will
require postmastectomy RT without an excessively high risk of flap
loss.
B. Immediate autologous reconstruction does not delay the administra-
tion of systemic chemotherapy and may be performed in patients with
stage II or III disease.
C. Skin-sparing mastectomy should be avoided because there is a 2% to
4% increase in the risk of local recurrence.
D. Patients undergoing autologous tissue reconstruction may still require
a complementary prosthetic implant to achieve a satisfactory cosmetic
result.Question 24.24. Which of the following factors is associated with failure to identify the
sentinel node?
A. Tumor located in the lower inner quadrant
B. Increased body mass index
C. Excisional biopsy before sentinel node biopsy (SNB)
D. Invasive lobular carcinomaQuestion 24.25. Which statement regarding SNB is TRUE?
A. SNB can be safely performed during pregnancy.
B. SNB is less accurate in patients with multicentric tumors.
C. The incidence of lymphedema is<2% at 12 months.
D. The false-negative rate in multicenter trials is∼10%.Question 24.26. Identify the CORRECT statement:
A. Radiation after BCS reduces the risk of local recurrence but does not
improve OS.
B. Radiation after BCS improves breast cancer-specific survival but does
not improve OS.
C. Radiation improves OS when administered after BCS but does not
improve OS in patients who underwent mastectomy.
D. Improved local control at 5 years results in a proportional improve-
ment in OS at 15 years.