Devita, Hellman, and Rosenberg's Cancer

LWBK1006-37 LWW-Govindan-Review November 24, 2011 11:29

488 DeVita, Hellman, and Rosenberg’s CANCER: Principles and Practice of Oncology Review

Question 37.5. Which imaging modality is the best tool to detect peritoneal recurrence?

A. Computed tomography (CT)

B. Magnetic resonance imaging (MRI)

C. Abdominal ultrasonogram

D. Positron emission tomography (PET)

Question 37.6. What is the most important adverse prognostic factor associated with

pseudomyxoma peritonei?

A. Presence of malignancy

B. Amount of mucin

C. Abdominal distention

D. Abdominal pain

Question 37.7. The features of disseminated peritoneal adenomucinosis (DPAM) include:

A. Peritoneal tumor

B. Scant cellularity

C. Abundant extracellular mucin

D. Low-grade endothelial cells

E. All of the above

Question 37.8. A 63-year-old patient presented with bowel obstruction and underwent

exploratory laparotomy that revealed a ruptured appendix with abun-

dant mucin. Scant, atypical cells without obvious malignant histology

were reported by the pathologist. What treatment plan results in the best

clinical outcome in this patient?

A. Maximal tumor debulking immediately followed by hyperthermic

intraperitoneal mitomycin C with or without 5FU and augmented

with adjuvant systemic therapy with 5FU and mitomycin C

B. Maximal tumor debulking followed by adjuvant systemic 5FU and

mitomycin C

C. Systemic 5FU and mitomycin C alone without surgical resection

D. Close observation

Question 37.9. Which of the following factors predicts the worst outcome in patients

with mucinous adenocarcinoma of appendix?

A. Histologic grade

B. Age

C. Performance status

D. The use of intraperitoneal therapy