Devita, Hellman, and Rosenberg's Cancer

LWBK1006-38 LWW-Govindan-Review December 12, 2011 20:29

Chapter 38•Immunosuppression-Related Malignancies 499

Question 38.8. How does the presentation of HIV-associated Hodgkin lymphoma (HL)

differ from that of HL in immunocompetent patients?

A. Patients with HIV-associated HL present at an older age.

B. B symptoms are rare in patients with HIV-associated HL.

C. Extranodal sites are less frequently involved in patients with HIV-

associated HL.

D. Mediastinal involvement is less frequent in patients with HIV-

associated HL.

Question 38.9. Which of the following is NOT correct regarding anogenital cancers in

patients infected with HIV?

A. In HIV-infected women with preinvasive cervical neoplasia, standard

therapy results in a twofold higher frequency of recurrence, compared

to their immunocompetent counterparts.

B. In patients with a CD4 count of less than 200/mm^3 , who are treated

with chemotherapy and radiation for invasive anal cancer, intractable

diarrhea is more common.

C. In patients with HIV, anal cancer and cervical cancer appear to be

unrelated to infection with human papilloma virus (HPV).

D. In women diagnosed with HIV infection, an initial PAP smear is rec-

ommended.

Question 38.10. Which of the following viruses are implicated in the development of can-

cers in patients with HIV infection?

A. EBV

B. Hepatitis C virus

C. Human herpes virus-8 (HHV-8)

D. All of the above