Devita, Hellman, and Rosenberg's Cancer

LWBK1006-42 LWW-Govindan-Review December 12, 2011 20:38

530 DeVita, Hellman, and Rosenberg’s CANCER: Principles and Practice of Oncology Review

Question 42.28. Autologous stem cell transplantation is indicated in which of the following

solid tumors?

A. Testicular cancer

B. Neuroblastoma

C. Breast cancer

D. A and B

Question 42.29. Graft manipulation ex vivo to purge contaminating tumor cells is a strat-

egy that has been successful in reducing the rate of relapse after autologous

stem cell transplantation.

A. True

B. False

Question 42.30. Autologous HCT is considered potentially curative in which of the fol-

lowing clinical scenarios?

A. Intermediate-grade non-Hodgkin’s lymphoma in chemotherapy-

sensitive first relapse

B. Multiple myeloma after complete response to initial therapy

C. Small lymphocytic lymphoma in second CR

D. Chemotherapy-sensitive metastatic breast carcinoma

Question 42.31. Which of the following is present in idiopathic pneumonia syndrome?

A. Associated with prior radiation therapy

B. Usually occurs more than 3 months after transplant

C. Rarely associated with CMV infection

D. A and C

Question 42.32. Which of the following is NOT a complication associated with autologous

HSCT?

A. Late incidence of myelodysplastic syndrome

B. Varicella zoster reactivation

C. Pneumocystis cariniipneumonia

D. Pericarditis