Devita, Hellman, and Rosenberg's Cancer

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LWBK1006-44 LWW-Govindan-Review November 24, 2011 11:30


Chapter 44•Management of Adverse Effects of Treatment 553

Question 44.8. Delayed CINV appears to be mostly related to which mechanism?
A. Substance P
B. Dopamine
C. 5HT
D. All of the above

Question 44.9. Agents commonly causing chemotherapy-induced diarrhea include all of
the following, EXCEPT:
A. Fluoropyrimidines
B. Platinum agents
C. Irinotecan
D. Taxanes

Question 44.10. A 50-year-old man with locally advanced pancreatic cancer presents with
intractable abdominal pain. His last bowel movement was 1 day prior.
His medications include pancrelipase and liquid morphine. His G-tube is
found to be functioning normally. Imaging reveals a mass arising from
the head of the pancreas, invading the superior mesenteric artery. A celiac
plexus block is performed. The following day, he complains of diarrhea
and his blood pressure is noted to be 89/60. His diarrhea is likely due to:
A. Pancreatic insufficiency
B. Enteral feedings
C. Celiac plexus block
D. All of the above

Question 44.11. The somatostatin analog octreotide has all of the following actions,
EXCEPT:
A. Suppresses inflammatory bowel disease
B. Suppresses release of insulin and vasoactive intestinal peptide
C. Reduces motility
D. Alters increased gastrointestinal absorption of water and electrolytes

Question 44.12. Agents commonly causing constipation in patients with cancer include all
of the following, EXCEPT:
A. Opioid analgesics
B. Antidepressants
C. Phenothiazine antiemetics
D. Diuretics

Question 44.13. Patient-related risk factors for stomatitis include which of the following?
A. Age more than 65 years or less than 20 years
B. Inadequate nutritional status
C. Exposure to oral stressors, including alcohol and smoking
D. All of the above
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