Devita, Hellman, and Rosenberg's Cancer

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LWBK1006-45 LWW-Govindan-Review December 13, 2011 15:32


Chapter 45•Supportive Care and Quality of Life 565

Question 45.20. Which of the following is TRUE about using anesthetic and neurosurgical
approaches to treat cancer pain?
A. Celiac ganglion block is effective in 50% of patients treated.
B. Peripheral nerve blocks are most useful in patients with somatic pain.
C. Cordotomy is almost always complicated by motor paresis.
D. Epidural local anesthetics delivered by continuous low-dose infusion
are useful long term for cancer pain.

Question 45.21. John eventually develops liver metastases and enters hospice care. His
elderly wife is unable to manage him at home, and he is transferred to
inpatient hospice after a few weeks. Eventually he becomes bed-bound
and mostly unresponsive. In the last 24 hours, his respirations are becom-
ing irregular, and he appears agitated, moaning, and restless. No recent
changes to his medications have been made. Appropriate management of
his condition includes:
A. Lorazepam 1 mg every 2 hours
B. Opioid drip to control dyspnea
C. Haldol 1 mg intravenously administered every 2 hours
D. All of the above

Question 45.22. Which of the following metabolic abnormalities in humans with cachexia
is TRUE?
A. Increased total body water
B. Increased serum lipid levels
C. Insulin resistance
D. All of the above

Question 45.23. What threshold is used to define critical weight loss in patients with
cancer?
A. 10% of baseline body weight in 6 months
B. 10% of lean body mass in 6 months
C. 10% of baseline body weight in 3 months
D. 10 lbs in 1 month

Question 45.24. Which of the following metabolic abnormalities is/are present in cancer
cachexia?
A. Increased gluconeogenesis
B. Decreased lipoprotein lipase activity
C. Decreased body glucose consumption
D. A and B

Question 45.25. Which of the following statements regarding dysgeusia is FALSE:
A. Taxanes have one of the strongest associations with dysgeusia.
B. Dysgeusia may be caused by depression.
C. Foods are better tolerated when they are thoroughly chewed prior to
ingestion.
D. Zinc may work best for sweet dysgeusia.
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