Devita, Hellman, and Rosenberg's Cancer

LWBK1006-47 LWW-Govindan-Review December 12, 2011 20:55

Chapter 47•Societal Issues in Oncology 583

Question 47.9. A 41-year-old woman is diagnosed with early-stage breast cancer. Genetic

testing reveals that she is BRCA1 mutation positive. She has two younger

sisters who are in their late 30s. What is the most appropriate action?

A. Call her sisters and request that they be tested for BRCA1 status.

B. Offer referral to a genetic counselor and provide informed consent

for testing.

C. Order mammograms for her sisters.

D. Recommend prophylactic mastectomy for her sisters.

Question 47.10. A study is undertaken to determine the timeliness of administration of

intravenous antibiotics for patients with cancer with fever and neutrope-

nia. This is an example of which type of quality measurement?

A. Process measure

B. Structural measure

C. Outcome measure

D. Technical measure

Question 47.11. What sources of data may be used for quality assessment?

A. Medical records

B. Administrative databases

C. Cancer registries

D. All of the above

Question 47.12. Strategies for implementing quality improvement include which of the

following?

A. Use of evidence-based guideline recommendations in clinical practice

B. Improvement in documentation of cancer care

C. Implementation of health information technology

D. All of the above

Question 47.13. Investigational New Drug (IND) applications are submitted to the Food

and Drug Administration (FDA) for review at which phase of develop-

ment?

A. Before phase I trials

B. Before phase II trials

C. Before phase III trials

D. After completion of a phase III trial demonstrating clear evidence of

efficacy