SCIENCE science.org 29 APRIL 2022 • VOL 376 ISSUE 6592 473-C
RESEARCHcatastrophic marine extinctions.
—SNV
Science, abe9039, this issue p. 524;
see also abo4259, p. 452
NEUROETHOLOGY
Bees want, too
In mammals, the subconscious
“wanting” of something, such as
food, is facilitated by a complex
neurobiological process that
involves dopaminergic signaling.
In a eusocial animal, such as the
honey bee, individuals supply
food not just for themselves but
also for their colony. Huang et
al. looked at the neurobiological
basis of wanting in honey bees
(Apis mellifera) and found
that it is also controlled by a
dopamine-based signaling
process, suggesting a shared
mechanism across millions
of years of divergence (see
the Perspective by Garcia and
Dyer). Furthermore, they found
that wanting was stimulated in
bees based on their own indi-
vidual desire to forage as well as
observation of the bee waggle
dance, suggesting the existence
of a colony-level motivation
mechanism. —SNV
Science, abn9920, this issue p. 508;
see also abp8609, p. 456
EPIDEMIOLOGY
The madness of dogs
Rabies is a deadly zoonotic
disease that causes tens of
thousands of deaths every year,
mainly among African and Asian
children. It is usually transmit-
ted to humans by dogs, and
once symptoms appear, it is
inevitably fatal. Despite control
efforts, rabies continues to
circulate at very low prevalence
in Serengeti district, Tanzania,
where Mancy et al. have been
tracking cases in several spe-
cies for more than a decade to
understand the dynamics of the
virus. Highly resolved genetic
data allowed the authors to trace
transmission networks, from
which individual dog behavior
emerges as a key factor (see
the Perspective by Antolin).
Some infected dogs may travel
long distances and introduce
new lineages into neighboring
communities, whereas others
may simply bite other animals.
Because dogs are mobile, culling
fails, and the only resort is fully
comprehensive dog vaccina-
tion. —CA
Science, abn0713, this issue p. 512;
see also abo7428, p. 453ORGANIC CHEMISTRY
Additive improvements
to nickel catalysis
It often takes decades of incre-
mental optimization to apply
chemical reactions beyond
the small range of substrates
studied at the discovery stage.
Prieto Kullmer et al. sought to
accelerate that optimization
process by screening a large,
diverse group of additives to a
cooperative nickel-photoredox
catalyst system. The screen
revealed that phthalimides
substantially expand the func-
tional compatibility of the nickel
catalyst and thus the substrate
scope. The phthalimide appears
to stabilize oxidative addition
complexes as well as break up
deactivated catalyst aggregates.
—JSY
Science, abn1885, this issue p. 532