SCIENCE science.org 29 APRIL 2022 • VOL 376 ISSUE 6592 435PHOTO: KIM TAYLOR/MINDEN PICTURES
RESEARCH
IN BRIEF
471 From Science and other journalsRESEARCH ARTICLES
474 Cancer
Stepwise-edited, human melanoma models
reveal mutations’ effect on tumor and
microenvironment
E. Hodis et al.
RESEARCH ARTICLE SUMMARY; FOR FULL TEXT:
DOI.ORG/10.1126/SCIENCE.ABI475 Dog genomics
Ancestry-inclusive dog genomics challenges
popular breed stereotypes K. Morrill et al.
RESEARCH ARTICLE SUMMARY; FOR FULL TEXT:
DOI.ORG/10.1126/SCIENCE.ABK476 Cancer
Cancer cells use self-inflicted DNA breaks to
evade growth limits imposed by genotoxic
stress B. D. Larsen et al.483 Neuroscience
Molecular and neural basis of pleasant touch
sensation B. Liu et al.491 Zeolites
In situ imaging of the sorption-induced
subcell topological flexibility of a rigid zeolite
framework H. Xiong et al.
PERSPECTIVE p. 457REPORTS
496 Dynamic genome
Dynamics of CTCF- and cohesin-mediated
chromatin looping revealed by live-cell
imaging M. Gabriele et al.502 Hydrogels
Piezoionic mechanoreceptors: Force-induced
current generation in hydrogels
Y. D o b a s h i et al.508 Neuroethology
Food wanting is mediated by transient
activation of dopaminergic signaling in the
honey bee brain J. Huang et al.
PERSPECTIVE p. 456ON THE COVER
Portraits of pet dogs exemplify the assortment
of physical characteristics seen in purebred and
mixed-breed dogs. Additionally, different breeds
are often thought to have distinctive behaviors
and personalities. However, data from thousands
of dogs involved in the Darwin’s Ark project reveal
that this is rarely true,
and that studying the full
diversity of dogs is the
best way to understand
interactions between
genetics, ancestry, and
complex traits such as
behavior. See page 475.
Photos: Elke VogelsangSCIENCE (ISSN 0036-8075) is published weekly on Friday, except last week in December, by the American Association for the Advancement of Science, 1200 New York Avenue, NW, Washington, DC 20005.Periodicals mail
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Science Careers ........................................ 540456 & 508
512 Epidemiology
Rabies shows how scale of transmission
can enable acute infections to persist at low
prevalence R. Mancy et al.
PERSPECTIVE p. 453; PODCAST517 Batteries
Dynamics of particle network in
composite battery cathodes J. Li et al.
PERSPECTIVE p. 455521 Gravitational waves
A gamma-ray pulsar timing array
constrains the nanohertz gravitational
wave background
The Fermi-LAT Collaboration524 Extinction
Avoiding ocean mass extinction from climate
warming J. L. Penn and C. Deutsch
PERSPECTIVE p. 452527 Organic chemistry
Scaffold hopping by net photochemical
carbon deletion of azaarenes
J. Woo et al.532 Organic chemistry
Accelerating reaction generality and
mechanistic insight through additive
mapping C. N. Prieto Kullmer et al.LETTERS468 Retraction
By R. L. Reyes et al.468 Evolutionary risks of osprey
translocations
By F. Monti et al.469 How to weaken Russian oil
and gas strength
By R. Hausmann et al.469 A global plastic treaty must
cap production
By M. Bergmann et al.470 ErrataDEPARTMENTS
437 Editorial
Removing a barrier to equity By A. Mapp542 Working Life
Scientist and artist By A. BashirBanca do Antfer
Telegram: https://t.me/bancadoantfer
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