6
ciplinary management team approach in the caring of the patients
and multidisciplinary research on the cancer. It is important for
the researchers to understand the current clinical and pathologi-
cal managements of patients with esophageal adenocarcinoma.
The knowledge of these provide the basic framework and materi-
als for research in this area. In addition, there are many molecular
tools available with preliminary data noted. The chapters in this
book will cover the protocols of all the abovementioned areas in
esophageal adenocarcinoma.
It is likely that these researches could help in understanding
more about the progression of the disease, increased the detection
of sensitive and specific predictive and prognostic maker as well as
finding of new target therapy for patients with esophageal
adenocarcinoma.References
- Lam KY, Ma L (1997) Pathology of esophageal
 cancers: local experience and current insights.
 Chin Med J 110:459–
- Rubenstein JH, Shaheen NJ (2015)
 Epidemiology, diagnosis, and management of
 esophageal adenocarcinoma. Gastroenterology
 149:302–
- Runge TM, Abrams JA, Shaheen NJ (2015)
 Epidemiology of Barrett’s esophagus and
 esophageal adenocarcinoma. Gastroenterol
 Clin North Am 44: 203–
- Lagergren J, Lagergren P (2013) Recent
 developments in esophageal adenocarcinoma.
 CA Cancer J Clin 63:232–
- Butt J, Kandel G (2014) Barrett esophagus:
 when to endoscope. Clin Endosc 47:40–
- Joo MK, Park JJ, Chun HJ (2018) Additional
 benefits of routine drugs on gastrointestinal
 cancer: statins, metformin, and proton pump
 inhibitors. Dig Dis 36:1–
- Beales IL, Dearman L, Vardi I, Loke Y (2016)
 Reduced risk of Barrett’s esophagus in statin
users: case-control study and meta-analysis.
Dig Dis Sci 61:238–- Gharahkhani P, Fitzgerald RC, Vaughan TL
 et al (2016) Genome-wide association studies
 in esophageal adenocarcinoma and Barrett’s
 esophagus: a large-scale meta-analysis. Lancet
 Oncol 17:1363–
- Kadota T, Fujii S, Oono Y, Imajoh M, Yano
 T, Kaneko K (2016) Adenocarcinoma aris-
 ing from heterotopic gastric mucosa in
 the cervical esophagus and upper thoracic
 esophagus: two case reports and literature
 review. Expert Rev Gastroenterol Hepatol
 10:405–
- Ning B, Abdelfatah MM, Othman MO
 (2017) Endoscopic submucosal dissection
 and endoscopic mucosal resection for early
 stage esophageal cancer. Ann Cardiothorac
 Surg 6:88–
- Barnes JA, Willingham FF (2015) Endoscopic
 management of early esophageal cancer. J Clin
 Gastroenterol 49:638–
Alfred K. Lam