Esophageal Adenocarcinoma Methods and Protocols

(sharon) #1
279


  1. Hong J, Resnick M, Behar J et al (2011) Role
    of Rac1 in regulation of NOX5-S function in
    Barrett’s esophageal adenocarcinoma cells. Am
    J Physiol Cell Physiol 301:C413–C420

  2. Beales IL, Ogunwobi OO (2009) Glycine-
    extended gastrin inhibits apoptosis in Barrett’s
    esophageal and esophageal adenocarcinoma
    cells through JAK2/STAT3 activation. J Mol
    Endocrinol 42:305–318

  3. Kebenko M, Drenckhan A, Gros SJ et al (2015)
    ErbB2 signaling activates the Hedgehog path-
    way via PI3K-Akt in human esophageal ade-
    nocarcinoma: identification of novel targets
    for concerted therapy concepts. Cell Signal
    27:373–381

  4. MacFarlane LA, Gu Y, Casson AG et al (2010)
    Regulation of fibroblast growth factor-2 by
    an endogenous antisense RNA and by argo-
    naute-2. Mol Endocrinol 24:800–812

  5. Pierini R, Kroon PA, Guyot S et al (2008) The
    procyanidin-mediated induction of apoptosis
    and cell-cycle arrest in esophageal adenocar-
    cinoma cells is not dependent on p21(Cip1/
    WAF1). Cancer Lett 270:234–241

  6. Rees JR, Onwuegbusi BA, Save VE (2006)
    In vivo and in vitro evidence for transform-
    ing growth factor-beta1-mediated epithelial to
    mesenchymal transition in esophageal adeno-
    carcinoma. Cancer Res 66:9583–9590

  7. Wang Z, Hao Y, Lowe AW (2008) The adeno-
    carcinoma-associated antigen, AGR2, promotes
    tumor growth, cell migration, and cellular
    transformation. Cancer Res 68:492–497

  8. Gentile A, Trusolino L, Comoglio PM (2008)
    The Met tyrosine kinase receptor in devel-
    opment and cancer. Cancer Metastasis Rev
    27:85–94

  9. Tuynman JB, Lagarde SM, Ten Kate FJ
    et al (2008) Met expression is an indepen-
    dent prognostic risk factor in patients with
    esophageal adenocarcinoma. Br J Cancer
    98:1102–1108

  10. Hack SP, Bruey JM, Koeppen H (2014) HGF/
    MET-directed therapeutics in gastresopha-
    geal cancer: a review of clinical and biomarker
    development. Oncotarget 5:2866–2880

  11. Jardim DL, de MeloGagliato D, Falchook
    GS et al (2014) MET aberrations and c-MET
    inhibitors in patients with gastric and esopha-


geal cancers in a phase I unit. Oncotarget
5:1837–1845


  1. Mesteri I, Schoppmann SF, Preusser M et al
    (2014) Overexpression of CMET is associ-
    ated with signal transducer and activator of
    transcription 3 activation and diminished
    prognosis in esophageal adenocarcinoma but
    not in squamous cell carcinoma. Eur J Cancer
    50:1354–1360

  2. Lennerz JK, Kwak EL, Ackerman A et al
    (2011) MET amplification identifies a small
    and aggressive subgroup of esophagogastric
    adenocarcinoma with evidence of responsive-
    ness to crizotinib. J Clin Oncol 29:4803–4810

  3. Watson GA, Zhang X, Stang MT et al (2006)
    Inhibition of c-Met as a therapeutic strategy
    for esophageal adenocarcinoma. Neoplasia
    8:949–955

  4. Anderson MR, Harrison R, Atherfold PA et al
    (2006) Met receptor signaling: a key effector in
    esophageal adenocarcinoma. Clin Cancer Res
    12:5936–5943

  5. Herrera LJ, El-Hefnawy T, Queiroz de
    Oliveira PE (2005) The HGF receptor c-Met is
    overexpressed in esophageal adenocarcinoma.
    Neoplasia 7:75–84

  6. Lockwood WW, Thu KL, Lin L et al (2012)
    Integrative genomics identified RFC3 as an
    amplified candidate oncogene in esopha-
    geal adenocarcinoma. Clin Cancer Res
    18:1936–1946

  7. Lyros O, Rafiee P, Nie L et al (2015) Wnt/β-
    Catenin signaling activation beyond robust
    nuclear β-Catenin accumulation in non dys-
    plastic Barrett’s esophagus: regulation via
    Dickkopf-1. Neoplasia 17:598–611

  8. Hong YS, Kim J, Pectasides E et al (2014) Src
    mutation induces acquired lapatinib resistance
    in ERBB2-amplified human gastresophageal
    adenocarcinoma models. PLoS One 9:e109440

  9. Aichler M, Elsner M, Ludyga N et al (2013)
    Clinical response to chemotherapy in esopha-
    geal adenocarcinoma patients is linked to
    defects in mitochondria. J Pathol 230:410–419

  10. Sims-Mourtada J, Izzo JG, Apisarnthanarax S
    et al (2006) Hedgehog: an attribute to tumor
    regrowth after chemoradiotherapy and a target
    to improve radiation response. Clin Cancer Res
    12:6565–6572


RNAi Gene Silencing and Esophageal Adenocarcinoma
Free download pdf