viii
17 Liquid Biopsy for Investigation of Cancer DNA in Esophageal
Adenocarcinoma: Cell-Free Plasma DNA and Exosome-Associated DNA ........... 187
Robert A. Smith and Alfred K. Lam
18 Somatic DNA Copy-Number Alterations Detection for Esophageal
Adenocarcinoma Using Digital Polymerase Chain Reaction ................................ 195
Katherine T. W. Lee, Vinod Gopalan, and Alfred K. Lam
19 Targeted Single Gene Mutation in Esophageal Adenocarcinoma ......................... 213
Katherine T. W. Lee, Robert A. Smith, Vinod Gopalan, and Alfred K. Lam
20 DNA Genome Sequencing in Esophageal Adenocarcinoma ................................ 231
Suja Pillai, Vinod Gopalan, and Alfred K. Lam
21 Epigenetics: DNA Methylation Analysis in Esophageal Adenocarcinoma ............. 247
Farhadul Islam, Johnny C. Tang, Vinod Gopalan, and Alfred K. Lam
22 Detection and Quantification of MicroRNAs
in Esophageal Adenocarcinoma .......................................................................... 257
Moein Amin, Farhadul Islam, Vinod Gopalan, and Alfred K. Lam
23 RNA Interference-Mediated Gene Silencing
in Esophageal Adenocarcinoma .......................................................................... 269
Farhadul Islam, Vinod Gopalan, and Alfred K. Lam
24 Proteomic Protocol in Esophageal Adenocarcinoma ........................................... 281
Peter Kelly
Index ................................................................................................................................. 295
Contents