92
Response to treatment.
Other pathologies.
SURGICAL MARGINS
Distance of carcinoma to:
Proximal margin.
Distal margin.
Circumferential margin.
LYMPH NODE STATUS
Number recovered and number involved by carcinoma.
ANCILLARY TESTS: Immunohistochemistry: HER2 status.References
- Mapstone NP (2007) Dataset for the histo-
pathological reporting of esophageal carci-
noma. The Royal College of Pathologists,
London - Lester S (2010) Manual of surgical pathology.
Saunders Elsevier, Philadelphia - Ibrahim N (2000) Guidelines for handling
esophageal biopsies and resection specimens
and their reporting. J Clin Pathol 53:89–94 - Kumarasinghe MP, Brown IS, Charlton A,
De Boer B, Eckstein R, Epari K, Gill A, Lam
A, Lauwers G, Raftopoulos S, Price T (2013)
Tumours of the esophagus and gastro-esoph-
ageal junction structured reported protocol,
1st edn, Published on web by Royal College
of Pathologists of Australasia. http://www.
rcpa.edu.au//Library/Practising-Pathology/
Structured-Pathology-Reporting-of-Cancer/
Cancer-Protocols - Lagarde S, ten Kate F, Reitsma J, Busch O, van
Lanschot J (2006) Prognostic factors in adeno-
carcinoma of the esophagus or gastresophageal
junction. J Clin Oncol 24:4347–4355 - Griffiths E, Brummell Z, Gorthi G, Pritchard
S, Welch I (2006) Tumor length as a prognos-
tic factor in esophageal malignancy: univariate
and multivariate survival analyses. J Surg Oncol
93:258–267 - Eloubeidi M, Desmond R, Arguedas M, Reed
C, Wilcox C (2009) Prognostic factors for the
survival of patients with esophageal carcinoma
in the U.S.: the importance of tumor length
and lymph node status. Cancer 95:1434–1443 - Deeter M, Dorer R, Kuppusamy M, Koehler
R, Low D (2009) Assessment of criteria and
clinical significance of circumferential resec-
tion margins in esophageal cancer. Arch Surg
144:618–624
9. Dexter S, Sue-Ling H, MCMahan M, Quirke P,
Mapstone N, Martin I (2001) Circumferential
resection margin involvement: an indepen-
dent predictor of survival following surgery for
esophageal cancer. Gut 48:667–670
10. Chang F, Deere H, Mahadeva U, George
S (2008) Histopathologic examination and
reporting of esophageal carcinomas following
preoperative neoadjuvant therapy: practical
guidelines and current issues. Am J Clin Pathol
129:252–262
11. Aida J, Vieth M, Ell C, May A, Pech O,
Hoshihara Y, Kumagai Y, Kawada K, Hishima
T, Taitishi Y, Sawabe M, Arai T, Matsuura M,
Takubo K (2011) Palisade vessels as a new
histologic marker of esophageal origin in ER
specimens from columnar-lined esophagus.
Am J Surg Pathol 35:1140–1145
12. Amin M, Edge S, Greene F, Byrd D, Brookland
R, Washington M, Gershenwald J, Compton
C, Hess K, Sullivan D, Jessup J, Brierley J,
Gaspar L, Schilsky R, Balch C, Winchester D,
Asare E, Madera M, Gress D, Meyer L (eds)
(2017) AJCC cancer staging manual, 8th edn.
Springer, New York
13. Allanson BM, Bonavita J, Mirzai B, Khor
T, Raftopoulos S, de Boer WB, Brown IS,
Kumarasinghe MP (2017) Early Barrett esoph-
agus-related neoplasia in segments 1cm or
longer is always associated with intestinal meta-
plasia. Mod Pathol 30:1170–1176
14. Rice T, Rusch V, Ishwaran H, Blackstone E
(2010) Cancer of the esophagus and esopha-
gogastric junction. Data-driven staging for
the seventh edition of the American Joint
Committee on Cancer/International Union
Against Cancer Cancer Staging Manuals.
Cancer 116:3763–3773
Benjamin M. Allanson and M. Priyanthi Kumarasinghe