The AHA Guidelines and Scientific Statements Handbook

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The AHA Guidelines and Scientifi c Statements Handbook


Classic claudication symptoms:
Muscle fatigue, cramping, or pain that reproducibly begins during exercise and
that promptly resolves with rest

Chart document the history of walking impairment (pain-free and total walking
distance) and specific lifestyle limitations

Document pulse examination

ABI less than or equal to 0.90

Confirmed PAD diagnosis

Go to Figure 9.5, Treatment of Claudication

Risk factor normalization:
Immediate smoking cessation
Treat hypertension: JNC-7 guidelines
Treat lipids: NCEP ATP III guidelines
Treat diabetes mellitus: HbAlc less than 7%*

Pharmacological risk reduction:
Antiplatelet therapy
(ACE inhibition;† Class IIa)

ABI

Exercise ABI
(TBI, segmental
pressure, or duplex
ultrasound
examination)

No PAD or
consider arterial
entrapment
syndromes

ABI greater
than 0.90

Abnormal
results

Normal
results

Fig. 9.4 Diagnosis of claudication and systemic risk treatment.



  • It is not yet proven that treatment of diabetes mellitus will signifi cantly reduce peripheral arterial disease (PAD)-specifi c (limb ischemic) endpoints. Primary
    treatment of diabetes mellitus should be continued according to established guidelines.
    † The benefi t of angiotensin-converting enzyme (ACE)-inhibition in individuals without claudication has not been specifi cally documented in prospective clinical
    trials, but has been extrapolated from other “at risk” populations.
    ABI, ankle-brachial index; HgbA1c, hemoglobin A; JNC-7, Seventh Report of the Joint National Committee on the Prevention, Detection, Evaluation, and Treatment
    of High Blood Pressure; LOE, level of evidence; NCEP ATP-III, National Cholesterol Education Program Adult Treatment Panel III.


Exercise and lower extremity pad rehabilitation
See Table 9.7.
Class I
1 A program of supervised exercise training is rec-
ommended as an initial treatment modality for
patients with intermittent claudication. (Level of
Evidence: A)
2 Supervised exercise training should be performed
for a minimum of 30 to 45 minutes, in sessions


performed at least three times per week for a
minimum of 12 weeks. (Level of Evidence: A)

Class IIb
The usefulness of unsupervised exercise programs is
not well established as an effective initial treatment
modality for patients with intermittent claudication.
(Level of Evidence: B)
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