Cannabinoids

Pharmacological Actions of Cannabinoids 15

Fig. 6.The structures of four nonclassical cannabinoids. The (+)-enantiomer of CP55940 is CP56667

Fig. 7.The structures ofR-(+)-WIN55212, JWH-015, AM1241, L-768242 and BML-190

ether (noladin ether) (Fig. 3) and several synthetic analogues of anandamide,

includingR-(+)-methanandamide, arachidonyl-2′-chloroethylamide (ACEA),

arachidonylcyclopropylamide (ACPA), O-689 and O-1812 (Fig. 8) (Howlett et

al. 2002; Pertwee 1999a; Porter et al. 2002).