Cannabinoids

Subject Index 767

OMDM-2 200
opioid 575, 577, 578, 582, 584, 585,
590
opioid systems 706
morphine 706
opioids 129
oral fluid 679

p42/44 MAP kinase 610
pain, 26–28, 118, 124, 125, 127, 159,
167, 169, 171, 221, 317, 318,
379, 498, 520, 574, 720, 723,
724, 726, 727, 729, 730, 731,
732, 734, 735, 745, 746, 748
palmitoylethanolamide (PEA)
6, 22, 27, 28, 35, 190, 582
palmitylsulfonyl fluoride (AM374)
191
Paracentrotus lividus 287
parallel fibers 355
paralytic ileus 574, 588
parasympathetic nervous system
345
Parkinson’s disease 483, 491, 495,
496, 728
PEA seepalmitoylethanolamide
pelvic neurons 319
perception 447
periaqueductal gray/grey 315, 337,
339, 528
perinatal exposure to cannabinoids
643–645, 648–652
and gene expression 648, 649,
651, 652
effects on maturation of neuro-
transmitter systems 643,
644, 648–652
sexual dimorphism 643, 649–
652
peripheralnervoussystem 345,346
peripheral vascular resistance 604,
610, 615, 616
peristalsis 577, 578, 580
peroxynitrite 64
pertussis toxin (PTX) 609, 611, 612
PET 426, 439, 449

pharmacokinetics 657

pharmacophore(s) 270

aminoalkylindole 265

classical CB side chain 256

classical/non-classicalCB 254

endogenous CB 259

pharmacophore development

ligand–ligand 252

ligand–receptor 252

phenolic hydroxyl 257

phenylmethylsulfonyl fluoride 191

phospholipase A 58

phospholipase C (PLC) 58, 288

phosphorylation 68

phylogenetic 284

phytocannabinoid(s) 2, 13, 17

pithed rabbits 346

pithed rats 346

PKA 56, 432

plant(s) 286, 287, 293, 294

plasma 672

platelets 616

PMSF 192, 197

polymorphism 99

positronemissiontomography(PET)

426, 439, 449

potassium channels 3, 22, 34, 36,

37, 329, 349, 356

prefrontal cortex 313

pregnancy 563, 566

pressure-volumeconductancesystem

604, 613

presynaptic inhibition

vesicle release machinery 350

presynaptic axon terminal 356

presynapticinhibition 333,338,349

calcium channels 349

mechanism 349

potassium channels 349

primaryamoebicmeningoencephali-

tis 399

primary humoral immune response

390

primary sensory fibres 337

progesterone 566

prokaryotic 284