List of Contents
PharmacologicalActionsofCannabinoids .................. 1
R.G. Pertwee
Cannabinoid Receptor Signaling........................ 53
A.C. Howlett
Molecular Biology of Cannabinoid Receptors................ 81
M.E. Abood
Analysis of the Endocannabinoid System
by Using CB 1 CannabinoidReceptorKnockoutMice............. 117
O. Valverde, M. Karsak, A. Zimmer
The Biosynthesis, Fate and Pharmacological Properties
of Endocannabinoids..... ......................... 147
V. Di Marzo, L. De Petrocellis, T. Bisogno
Modulators of Endocannabinoid Enzymic Hydrolysis
andMembraneTransport ........................... 187
W.-S.V. Ho, C.J. Hillard
Structural Requirements for Cannabinoid Receptor Probes......... 209
G.A. Thakur, S.P. Nikas, C. Li, A. Makriyannis
Cannabinoid Receptors and Their Ligands: Ligand–Ligand
and Ligand–Receptor Modeling Approaches................. 247
P.H. Reg g io
The Phylogenetic Distribution and Evolutionary Origins
of Endocannabinoid Signalling........................ 283
M.R. Elphick, M. Egertová
Distribution of Cannabinoid Receptors in the Central
andPeripheralNervousSystem ........................ 299
K. Mackie
EffectsofCannabinoidsonNeurotransmission ............... 327
B. Szabo, E. Schlicker