Patient_Reported_Outcome_Measures_in_Rheumatic_Diseases

37

Development of PROMs Instrument

Figure 2.6 illustrates different steps in development of a PROM instrument. The
proposed steps are generated from different resources.

Steps in Developing a PROM Instrument

Step I: Conceptual Framework Construction

1. Establishing the need for a new measure by reviewing previous literature.


2. Defining the targeted population in terms of characteristics and accessibility.

Concept

Domain-2

Domain-3

Domain-1

Item-1

Item-2

Item-3

Item-1

Item-2

Item-3

Item-1

Item-2

Item-3

Fig. 2.4 Conceptual framework for a PROM instrument development displaying three domains
and corresponding items

Disease Treatment

Biochemical Tests

(Non PRO Measure)

Physical

Examination

(Non PRO Measure)

Symptoms of

Diseases or QoL

(PRO Meassure)

Fig. 2.5 End-point model diagram displaying different outcome measures in response to a spe-
cific treatment including PROM

2 A Guide to PROMs Methodology and Selection Criteria