Clinical_Rounds_in_Endocrinology_Volume_II_-_Pediatric_Endocrinology

223 What are the genes implicated in the development and migration of both olfac- tory and GnRH neurons? The genes responsible ...

224 Therefore, any insult during development or migration of these neurons result in anosmia and hypogonadotropic hypogonadism. ...

225 corticospinal fibers, lack of inter-hemispheric inhibition between the two motor cortices, and functional defects in motor p ...

226 penis. Therefore, accurate measurement of stretched penile length should be done prior to subjecting a child for evaluation ...

227 What are the hormones responsible for prepubertal penile growth? During intrauterine period, there is an increase in penil ...

228 How to investigate a child with delayed puberty? The first-line investigations in a child presenting with delayed puberty ...

229 should also be done as it may help in differentiating between CDGP and hypo- gonadotropic hypogonadism. Further evaluation i ...

230 How to define reversible congenital isolated hypogonadotropic hypogonadism? Reversible congenital isolated hypogonadotropi ...

231 A 15-year-old boy presented with delayed puberty. His height was 156 cm (at 3 rd percentile, with target height of 173 cm, ...

232 Fig. 7.12 (a) A 14-year-old boy with short stature and delayed puberty with bilateral testicular volume of 3 ml. Note bilate ...

233 c Fig. 7.12 (continued) 7 Delayed Puberty ...

234 Does CDGP and congenital idiopathic hypogonadotropic hypogonadism represent a spectrum of a common disorder? A strong famil ...

235 What are the diagnostic tests to differentiate between CDGP and congenital IHH? The diagnostic tests that help to different ...

236 month for a period of 3 months. With this therapy, there is an increase in testicu- lar volume by 3–4 ml in 6–9 months, prog ...

237 spermatogenesis at puberty, and this effect of LH is mediated by increase in intratesticular testosterone. However, once ini ...

238 What is the utility of FSH in the induction of puberty in boys with congenital IHH? The aim of therapy in a patient with co ...

239 What is the most common therapy to induce puberty in boys with congenital IHH? Exogenous testosterone is the most common th ...

240 intramuscular preparations of testosterone like enanthate, propionate, or cypi- onate are preferred for induction of puberty ...

241 monitored and maintained in the eugonadal range. After 6–12 months of ini- tiation of hCG therapy with serum testosterone in ...

242 What is Klinefelter’s syndrome? Klinefelter’s syndrome (KFS) is characterized by small testes, gynecomastia, long-leggedne ...