Clinical_Rounds_in_Endocrinology_Volume_II_-_Pediatric_Endocrinology

17 2

respectively. Basal serum estradiol was 23.7 pg/ml. The dose of depot leuprolide
was increased to 7.5 mg once a month and advised to have a regular follow-up at
three monthly intervals (Fig. 6.1).

a

b

c

Fig. 6.1 (a) A 3-year-old child presented with thelarche (B 3 ), (b) X-ray of wrist showing bone age of
7 years, (c) CEMRI sella showing convex upper border of the pituitary (red arrow) suggestive of GDPP

6 Precocious Puberty