Clinical_Rounds_in_Endocrinology_Volume_II_-_Pediatric_Endocrinology

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an undervirilized 46,XY DSD, dorsal part of penis (corpora cavernosa) out-
grows the ventral part (corpora spongiosa and penile urethra), thereby resulting
in chordee.


  1. What is cryptorchidism?


Cryptorchidism is defi ned as failure of one or both testis to descend into the
scrotum. The undescended testes may lie anywhere along its route of descent
from abdomen to scrotum or it may be ectopically placed. The prevalence of
cryptorchidism in term newborn boys weighing >2.5 Kg varies between 1.8 %
and 3.8 %. Spontaneous descent of testis occurs in majority of these infants
(50–70 %) by 1–3 months of age, whereas spontaneous descent beyond
6–9 months is rare. The prevalence of cryptorchidism is only approximately
0.8 % at 1 year of age. Cryptorchidism is unilateral in approximately 80 %,
whereas the rest have bilateral undescended testes. The most common site of
undescended testes is high scrotal/pre-scrotal (48 %), followed by superfi cial
inguinal ring (29 %), inguinal canal (22 %), and abdomen (<1 %). Ectopic testes
contribute to <1 % of all cases of cryptorchidism and the sites of ectopic testes
include just above penis (pre-penile), perineum, femoral canal, and intra-
abdominal wall (Fig. 9.8 ).

Normal

High scrotal

Inguinal canal

Abdominal

Fig. 9.8 Common sites of
undescended testes


9 Disorders of Sex Development
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