Clinical_Rounds_in_Endocrinology_Volume_II_-_Pediatric_Endocrinology

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Fig. 11.1 (a) A 42-year-old male presented with proptosis. (b) CEMRI sella showing giant pitu-
itary adenoma. (c) CECT abdomen showing 1 × 1 cm isodense lesion in the head of the pancreas.
(d) CECT abdomen depicting bilateral adrenal enlargement. (e) 99mTc sestamibi scan displaying
tracer uptake in the right superior, left superior, and inferior parathyroid glands. (f) SPECT-CT
fusion image showed increased tracer uptake in the left superior parathyroid gland. (g)
Chromatogram demonstrated duplication of C1546 gene in exon 10 and frame-shift mutation at
P-Arg 516 consistent with MEN1 syndrome

11 Multiple Endocrine Neoplasia