b2815 Tissue Engineering and Nanotheranostics “9.61x6.69”
vi Preface
Tissue engineering has advanced into clinical settings such as stem
cell neuron repair, bio-resorbable stent, and tissue-engineered carti-
lage. Current tissue engineering research uses computer simulation
and 3D printing technologies advancing the state-of-the-art in an
unprecedented fashion.
The first chapter of the book discusses the status of obtaining
skeletal muscle that may be lost due to diseases and injuries. Some
of the research highlights are described in Chapter 2 on biomate-
rial-based patches as fetal surgery implants. The authors give
detailed experimental results on implant development for open
fetal surgery and fetoscopic applications. They also discuss the
internal environment surrounding the fetus in terms of pH
changes, mechanical impact, and degradation profiles. Chapter 3
updates the status in 3D printing for cartilage regeneration.
Articular cartilage is introduced with various unique biological
features in comparison to most common tissues. Chapter 4 focuses
on a fascinating topic regarding differentiation of human pluripo-
tent stem cells. In particular, this chapter deals with the aspects of
human pluripotent stem cells for therapeutic applications. Critical
issues in this area are discussed including the difficulties involved
in differentiating human pluripotent stem cells from diseases-
related cell lineages, including neurons, cardiac muscle cells and
pancreatic beta cells.
The remainder of the book considers issues in nanomedicine with
an emphasis on bio-imaging, bio-sensing, nanodelivery, and multi-
functional nanocarriers for cancer thereanostics. Some effective
means of nano therapy involving the photothermal effect is also
introduced.
Chapter 5 describes recent progress on the development of mag-
netic nanohybrids for MRI and phototherapy. The authors have car-
ried out extensive experiments on developing novel nanomaterials
are particularly effective for early detection of premature tumor and
proper treatment. Chapter 6 summarizes some of the key develop-
ments in biosensing and imaging. Several conducting nanoparticles
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