Tissue Engineering And Nanotheranostics

(Steven Felgate) #1
b2815 Tissue Engineering and Nanotheranostics “9.61x6.69”

vi Preface

Tissue engineering has advanced into clinical settings such as stem


cell neuron repair, bio-resorbable stent, and tissue-engineered carti-


lage. Current tissue engineering research uses computer simulation


and 3D printing technologies advancing the state-of-the-art in an


unprecedented fashion.


The first chapter of the book discusses the status of obtaining


skeletal muscle that may be lost due to diseases and injuries. Some


of the research highlights are described in Chapter 2 on biomate-


rial-based patches as fetal surgery implants. The authors give


detailed experimental results on implant development for open


fetal surgery and fetoscopic applications. They also discuss the


internal environment surrounding the fetus in terms of pH


changes, mechanical impact, and degradation profiles. Chapter 3


updates the status in 3D printing for cartilage regeneration.


Articular cartilage is introduced with various unique biological


features in comparison to most common tissues. Chapter 4 focuses


on a fascinating topic regarding differentiation of human pluripo-


tent stem cells. In particular, this chapter deals with the aspects of


human pluripotent stem cells for therapeutic applications. Critical


issues in this area are discussed including the difficulties involved


in differentiating human pluripotent stem cells from diseases-


related cell lineages, including neurons, cardiac muscle cells and


pancreatic beta cells.


The remainder of the book considers issues in nanomedicine with


an emphasis on bio-imaging, bio-sensing, nanodelivery, and multi-


functional nanocarriers for cancer thereanostics. Some effective


means of nano therapy involving the photothermal effect is also


introduced.


Chapter 5 describes recent progress on the development of mag-


netic nanohybrids for MRI and phototherapy. The authors have car-


ried out extensive experiments on developing novel nanomaterials


are particularly effective for early detection of premature tumor and


proper treatment. Chapter 6 summarizes some of the key develop-


ments in biosensing and imaging. Several conducting nanoparticles


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