Innovations_in_Molecular_Mechanisms_and_Tissue_Engineering_(Stem_Cell_Biology_and_Regenerative_Medicine)

(Brent) #1
117


  1. Zhao T, Zhang Z-N, Rong Z, Xu Y (2011) Immunogenicity of induced pluripotent stem cells.
    Nature 474(7350):212–215. doi: 10.1038/nature10135

  2. Xie M, Cao N, Ding S (2014) Small molecules for cell reprogramming and heart repair:
    progress and perspective. ACS Chem Biol 9(1):34–44. doi: 10.1021/cb400865w

  3. Zhou H, Wu S, Joo JY et al (2009) Generation of induced pluripotent stem cells using recom-
    binant proteins. Cell Stem Cell 4(5):381–384. doi: 10.1016/j.stem.2009.04.005

  4. Ieda M, Tsuchihashi T, Ivey KN et al (2009) Cardiac fi broblasts regulate myocardial prolif-
    eration through beta1 integrin signaling. Dev Cell 16(2):233–244. doi: 10.1016/j.
    devcel.2008.12.007

  5. Qian L, Huang Y, Spencer CI et al (2012) In vivo reprogramming of murine cardiac fi bro-
    blasts into induced cardiomyocytes. Nature 485(7400):593–598. doi: 10.1038/nature11044

  6. Song K, Nam Y-J, Luo X et al (2012) Heart repair by reprogramming non-myocytes with
    cardiac transcription factors. Nature 485(7400):599–604. doi: 10.1038/nature11139

  7. Srivastava D, Ieda M, Fu J, Qian L (2012) Cardiac repair with thymosin β4 and cardiac repro-
    gramming factors. Ann N Y Acad Sci 1270:66–72. doi: 10.1111/j.1749-6632.2012.06696.x

  8. Wang H, Cao N, Spencer CI et al (2014) Small molecules enable cardiac reprogramming of
    mouse fi broblasts with a single factor, Oct4. Cell Rep 6(5):951–960. doi: 10.1016/j.
    celrep.2014.01.038

  9. Jayawardena TM, Egemnazarov B, Finch EA et al (2012) MicroRNA-mediated in vitro and
    in vivo direct reprogramming of cardiac fi broblasts to cardiomyocytes. Circ Res
    110(11):1465–1473. doi: 10.1161/CIRCRESAHA.112.269035

  10. Nam Y-J, Song K, Luo X et al (2013) Reprogramming of human fi broblasts toward a cardiac
    fate. Proc Natl Acad Sci U S A 110(14):5588–5593. doi: 10.1073/pnas.1301019110

  11. Zhou H, Dickson ME, Kim MS, Bassel-Duby R, Olson EN (2015) Akt1/protein kinase B
    enhances transcriptional reprogramming of fi broblasts to functional cardiomyocytes. Proc
    Natl Acad Sci U S A 112(38):11864–11869. doi: 10.1073/pnas.1516237112

  12. Zhao Y, Londono P, Cao Y et al (2015) High-effi ciency reprogramming of fi broblasts into
    cardiomyocytes requires suppression of pro-fi brotic signalling. Nat Commun 6:8243.
    doi: 10.1038/ncomms9243

  13. Nagalingam RS, Safi HA, Czubryt MP (2015) Gaining myocytes or losing fi broblasts: chal-
    lenges in cardiac fi broblast reprogramming for infarct repair. J Mol Cell Cardiol 93:108–114.
    doi: 10.1016/j.yjmcc.2015.11.029

  14. Zhang Y, Cao N, Huang Y et al (2016) Expandable cardiovascular progenitor cells repro-
    grammed from fi broblasts. Cell Stem Cell 18(3):368–381. doi: 10.1016/j.stem.2016.02.010

  15. Nag AC, Cheng M (1986) Biochemical evidence for cellular dedifferentiation in adult rat
    cardiac muscle cells in culture: expression of myosin isozymes. Biochem Biophys Res
    Commun 137(2):855–862

  16. Zhang Y, Li T-S, Lee S-T et al (2010) Dedifferentiation and proliferation of mammalian
    cardiomyocytes. PLoS One 5(9), e12559. doi: 10.1371/journal.pone.0012559

  17. Zhang Y, Zhong JF, Qiu H et al (2015) Epigenomic reprogramming of adult cardiomyocyte-
    derived cardiac progenitor cells. Sci Rep 5:17686. doi: 10.1038/srep17686

  18. Li T-S, Cheng K, Lee S-T et al (2010) Cardiospheres recapitulate a niche-like microenviron-
    ment rich in stemness and cell-matrix interactions, rationalizing their enhanced functional
    potency for myocardial repair. Stem Cells 28(11):2088–2098. doi: 10.1002/stem.532

  19. Malliaras K, Makkar RR, Smith RR et al (2014) Intracoronary cardiosphere-derived cells
    after myocardial infarction: evidence of therapeutic regeneration in the fi nal 1-year results of
    the CADUCEUS trial (CArdiosphere-Derived autologous stem cells to reverse ventricUlar
    dySfunction). J Am Coll Cardiol 63(2):110–122. doi: 10.1016/j.jacc.2013.08.724

  20. Makkar RR, Smith RR, Cheng K et al (2012) Intracoronary cardiosphere-derived cells for
    heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised
    phase 1 trial. Lancet 379(9819):895–904. doi: 10.1016/S0140-6736(12)60195-0

  21. Ibrahim AG-E, Cheng K, Marbán E (2014) Exosomes as critical agents of cardiac regeneration
    triggered by cell therapy. Stem Cell Reports 2(5):606–619. doi: 10.1016/j.stemcr.2014.04.006


6 Cellular Approaches to Adult Mammalian Heart Regeneration

Free download pdf