163
- Gao L, Díaz-Corrales FJ, Carrillo F et al (2010) Brain-derived neurotrophic factor G196A
polymorphism and clinical features in Parkinson’s disease. Acta Neurol Scand 122:41–45.
doi: 10.1111/j.1600-0404.2009.01253.x - Hyman C, Hofer M, Barde YA et al (1991) BDNF is a neurotrophic factor for dopaminergic
neurons of the substantia nigra. Nature 350:230–232. doi: 10.1038/350230a0 - Zhang S, Liu X, Liu Z et al (2009) Stem cells modifi ed by brain-derived neurotrophic factor
to promote stem cells differentiation into neurons and enhance neuromotor function after
brain injury. Chinese J Traumatol English Ed 12:195–199. doi: 10.3760/cma.j.issn.1008-
1275.2009.04.001 - Zhang Y, Pardridge WM (2006) Blood-brain barrier targeting of BDNF improves motor func-
tion in rats with middle cerebral artery occlusion. Brain Res 1111:227–229. doi: 10.1016/j.
brainres.2006.07.005 - Pardridge WM (2002) Blood-brain barrier drug targeting enables neuroprotection in brain
ischemia following delayed intravenous administration of neurotrophins. In: Alzheimer C
(ed) Neuroprotection CNS. Mol Cell Biol, Springer, Boston, pp 397–430 - Ma H, Yu B, Kong L et al (2012) Neural stem cells over-expressing brain-derived neuro-
trophic factor (BDNF) stimulate synaptic protein expression and promote functional recovery
following transplantation in rat model of traumatic brain injury. Neurochem Res 37:69–83.
doi: 10.1007/s11064-011-0584-1 - Blits B, Oudega M, Boer G et al (2003) Adeno-associated viral vector-mediated neurotrophin
gene transfer in the injured adult rat spinal cord improves hind-limb function. Neuroscience
118:271–281. doi: 10.1016/S0306-4522(02)00970-3 - Xu XM, Guénard V, Kleitman N et al (1995) A combination of BDNF and NT-3 promotes
supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord. Exp
Neurol 134:261–272. doi: 10.1006/exnr.1995.1056 - Bamber NI, Li H, Lu X et al (2001) Neurotrophins BDNF and NT-3 promote axonal re-entry
into the distal host spinal cord through Schwann cell-seeded mini-channels. Eur J Neurosci
13:257–268. doi: 10.1111/j.1460-9568.2001.01387.x - Xu XM, Zhang S-X, Li H et al (1999) Regrowth of axons into the distal spinal cord through
a Schwann-cell-seeded mini-channel implanted into hemisected adult rat spinal cord. Eur
J Neurosci 11:1723–1740. doi: 10.1046/j.1460-9568.1999.00591.x - Azim K, Raineteau O, Butt AM (2012) Intraventricular injection of FGF-2 promotes genera-
tion of oligodendrocyte-lineage cells in the postnatal and adult forebrain. Glia 60:1977–1990.
doi: 10.1002/glia.22413 - Bansal R, Lakhina V, Remedios R, Tole S (2003) Expression of FGF receptors 1, 2, 3 in the
embryonic and postnatal mouse brain compared with Pdgfralpha, Olig2 and Plp/dm20: impli-
cations for oligodendrocyte development. Dev Neurosci 25:83–95. - Timmer M, Cesnulevicius K, Winkler C et al (2007) Fibroblast growth factor (FGF)-2 and
FGF receptor 3 are required for the development of the substantia nigra, and FGF-2 plays a
crucial role for the rescue of dopaminergic neurons after 6-hydroxydopamine lesion.
J Neurosci 27:459–471. doi: 10.1523/JNEUROSCI.4493-06.2007 - Butt AM, Dinsdale J (2015) Opposing actions of fi broblast growth factor-2 on early and late
oligodendrocyte lineage cells in vivo. J Neuroimmunol 166:75–87. doi: 10.1016/j.
jneuroim.2005.05.015 - Tabata Y (2009) Biomaterial technology for tissue engineering applications. J R Soc Interface
6(Suppl 3):S311–S324. doi: 10.1098/rsif.2008.0448.focus - Rooney GE, Vaishya S, Ameenuddin S et al (2008) Rigid fi xation of the spinal column
improves scaffold alignment and prevents scoliosis in the transected rat spinal cord. Spine
(Phila Pa 1976) 33:E914–E919. doi: 10.1097/BRS.0b013e318186b2b1 - Tasdemiroglu E, Tibbs PA (1995) Long-term follow-up results of thoracolumbar fractures
after posterior instrumentation. Spine (Phila. Pa. 1976). 20:1704–1708 - Wang J, Zheng J, Zheng Q et al (2015) FGL-functionalized self-assembling nanofi ber hydro-
gel as a scaffold for spinal cord-derived neural stem cells. Mater Sci Eng C Mater Biol Appl
46:140–147. doi: 10.1016/j.msec.2014.10.019
7 Regenerative Strategies for the Central Nervous System