172
- Osaka M, Honmou O, Murakami T et al (2010) Intravenous administration of mesenchymal
stem cells derived from bone marrow after contusive spinal cord injury improves functional
outcome. Brain Res 1343:226–235. doi: 10.1016/j.brainres.2010.05.011 - Karussis D, Kassis I, Kurkalli BGS, Slavin S (2008) Immunomodulation and neuroprotection
with mesenchymal bone marrow stem cells (MSCs): a proposed treatment for multiple scle-
rosis and other neuroimmunological/neurodegenerative diseases. J Neurol Sci 265:131–135.
doi: 10.1016/j.jns.2007.05.005 - Titomanlio L, Kavelaars A, Dalous J et al (2011) Stem cell therapy for neonatal brain injury:
Perspectives and Challenges. Ann Neurol 70:698–712. doi: 10.1002/ana.22518 - Syková E, Jendelová P, Urdzíková L, et al. Bone marrow stem cells and polymer hydrogels–
two strategies for spinal cord injury repair. Cell Mol Neurobiol 26:1113–1129. doi: 10.1007/
s10571-006-9007-2 - van Velthoven CTJ, Kavelaars A, van Bel F, Heijnen CJ (2010) Repeated mesenchymal stem
cell treatment after neonatal hypoxia-ischemia has distinct effects on formation and matura-
tion of new neurons and oligodendrocytes leading to restoration of damage, corticospinal
motor tract activity, and sensorimotor function. J Neurosci 30:9603–9611. doi: 10.1523/
JNEUROSCI.1835-10.2010 - Mahmood A, Lu D, Chopp M (2004) Marrow stromal cell transplantation after traumatic
brain injury promotes cellular proliferation within the brain. Neurosurgery 55 - Okazaki T, Magaki T, Takeda M et al (2008) Intravenous administration of bone marrow stro-
mal cells increases survivin and Bcl-2 protein expression and improves sensorimotor function
following ischemia in rats. Neurosci Lett 430:109–114. doi: 10.1016/j.neulet.2007.10.046 - Quertainmont R, Cantinieaux D, Botman O et al (2012) Mesenchymal stem cell graft
improves recovery after spinal cord injury in adult rats through neurotrophic and pro-
angiogenic actions. PLoS One 7, e39500. doi: 10.1371/journal.pone.0039500 - Ide C, Nakai Y, Nakano N et al (2010) Bone marrow stromal cell transplantation for treatment of
sub-acute spinal cord injury in the rat. Brain Res 1332:32–47. doi: 10.1016/j.brainres.2010.03.043 - Franssen EHP, de Bree FM, Verhaagen J (2007) Olfactory ensheathing glia: their contribution
to primary olfactory nervous system regeneration and their regenerative potential following
transplantation into the injured spinal cord. Brain Res Rev 56:236–258. doi: 10.1016/j.
brainresrev.2007.07.013 - Raisman G, Li Y (2007) Repair of neural pathways by olfactory ensheathing cells. Nat Rev
Neurosci 8:312–319. doi: 10.1038/nrn2099 - Ramón-Cueto A, Plant GW, Avila J, Bunge MB (1998) Long-distance axonal regeneration in
the transected adult rat spinal cord is promoted by olfactory ensheathing glia transplants.
J Neurosci 18:3803–3815 - Li Y (1997) Repair of adult rat corticospinal tract by transplants of olfactory ensheathing
cells. Science 277:2000–2002. doi: 10.1126/science.277.5334.2000 - Fouad K, Schnell L, Bunge MB et al (2005) Combining Schwann cell bridges and olfactory-
ensheathing glia grafts with chondroitinase promotes locomotor recovery after complete tran-
section of the spinal cord. J Neurosci 25:1169–1178. doi: 10.1523/JNEUROSCI.3562-04.2005 - Hospital CMU Implantation of olfactor ensheathing cells (OECs) (2011) In: ClinicalTrials.
gov [Internet]. National Library of Medicine, Bethesda. https://clinicaltrials.gov/ct2/show/
NCT02034669. Accessed 27 Jan 2016 - Wroclaw Medical University Transplantation of Autologous Olfactor Ensheathing Cells in
Complete Human Spinal Cord Injury (2010) In: ClinicalTrials.gov [Internet]. National
Library of Medicine, Bethesda. https://clinicaltrials.gov/ct2/show/NCT0123. Accessed 27
Jan 2016 - Leu S, Lin Y-C, Yuen C-M et al (2010) Adipose-derived mesenchymal stem cells markedly
attenuate brain infarct size and improve neurological function in rats. J Transl Med 8:63.
doi: 10.1186/1479-5876-8-63 - Ra JC, Shin IS, Kim SH et al (2011) Safety of intravenous infusion of human adipose tissue-
derived mesenchymal stem cells in animals and humans. Stem Cells Dev 20:1297–1308.
doi: 10.1089/scd.2010.0466
A. Roussas et al.