178
Heart failure
cardiomyocytes , 101
cardiomyopathies , 101
cell death , 102
chronic , 102
complication , 101
ischemic reperfusion , 102
myocardial remodeling , 102
syndrome , 101
Heart regeneration , 104–112
amphibian blastema , 103
autologous cellular approaches , 106
cardiac circulation , 104
cardiomyocyte dedifferentiation , 103
cellular plasticity , 103
cytokinesis , 103 , 104
developments
BMCs , 107
cardiomyocyte proliferation , 110 , 111
cardiomyocytes , 105
cell division , 105
CPCs , 105–107
dedifferentiation, adult
cardiomyocytes , 110
direct reprogramming , 109–110
engraftment , 111 , 112
ES cells , 108
iPS cells , 109
myocardial infarction , 105
neonatal mouse hearts , 104
tissue mechanics , 111
ductus arteriosus , 104
epicardial signaling , 102
extracellular matrix protein expression , 103
fi bronectin , 102
genetic lineage tracing , 103
heart failure , 101–102
immunostaining , 103
mosaic analysis with double markers
(MADM) , 104
neomyogenic capacity , 103
neonatal , 103
newt and axolotl , 103
regenerative capacity , 102
transdifferentiation , 103
zebrafi sh , 102
High proliferation index , 82
Histolysis of mature stump tissue , 96 , 97
Homeostasis , 94
Human fi ngertip regeneration , 80
Human mesenchymal stem cells (HMSCs) , 135
Human microvascular endothelial cells
(HMVEC) , 90
Human stem cells for cartilage regeneration , 71
Hyaline cartilage , 58 , 60 , 66
Hyaluronan , 58 , 72
Hyperbaric oxygen (HBO) treatment , 94–97
Hypertrophic chondrocytes , 59 , 85
Hypertrophy , 59 , 60 , 63 , 67
Hypoxia , 95 , 96
Hypoxia inducing factor , 95
Hypoxic microenvironment , 94 , 96
Hypoxic zone , 94
Hypoxyprobe-1 Plus , 94 , 95I
IL-1β. See Interleukin-1β (IL-1β)
Immunohistochemical localization , 94
Immunohistochemical studies , 89 , 96
Immunostaining , 87 , 90 , 95
Indian hedgehog (Ihh) , 72
Induced pluripotent stem cells (iPSCs) , 70 , 72 ,
109 , 110
Induced regeneration , 83–86 , 88
Injury-induced re-amputation , 82
Injury-induced secondary amputation , 80
In-situ hybridization , 85 , 89
Intercellular signaling , 94
Interleukin-1β (IL-1β) , 127 , 128
Intramembranous ossifi cation , 82 , 84
Intrinsic articular cartilage repair , 66 , 67
Invading osteoclasts , 60
iPS cells. See Induced pluripotent stem cells
(iPSCs)K
Keratin sulfate , 58L
Lateral plate mesoderm , 61
Limb and tail regeneration , 60–64
Limb cartilage , 59
Lizard , 62–65 , 67 , 72
Lizard regeneration , 28 , 29
A. carolinensis tail regeneration , 26
appendages , 23
autotomy , 24
blastema formation , 26
cell proliferation , 26
ependymal cells , 28
extracellular matrix , 25
fi brosis , 25
genomicIndex