Spectrum biology

(Axel Boer) #1

  1. Which one of the following is wrongly matched?
    [CBSE AIPMT 2014]
    (a)Transcription — Writing information from DNA to tRNA
    (b)Translation — Using information in mRNA to make
    protein
    (c)Repressor — Binds to operator to stop enzyme
    protein synthesis
    (d)Operon — Structural genes, operator and promoter

  2. Find the wrongly matched pair. [Kerala CEE 2014]
    (a)Har Govind Khorana — Synthesised RNA
    molecules chemically
    (b)George Gamow — Codon is triplet
    (c)Meselson and StahI —Regulation of gene expression
    (d)Alec Jeffreys — DNA fingerprinting

  3. A geneticist isolates a gene for a specific trait under
    study. And also the corresponding mRNA. She found
    that the mRNA contains 1000 fewer bases than the
    DNA sequence. Did she isolate the wrong DNA?
    (a)Yes, mRNA is made from DNA template and should be the
    same length as DNA sequence.
    (b)Yes, the mRNA should contain more bases than the DNA
    sequence because bases flanking the gene are also
    transcribed.
    (c)No, the final mRNA contains only exons, the introns were
    removed.
    (d)No, the mRNA was partially degraded after it was
    transcribed.

  4. The newly synthesised mRNA undergoes few
    modifications before undergoing translation. In the
    absence of which of the changes it is unable to undergo
    translation
    (a) 5 ′ guanosine cap (b) poly A tail
    (c) snRNPs (d) None of these

  5. The DNA from the bacteriophage φ× 174 has a base
    composition of 25% A. 33% T, 24% G and 18% C, which
    of the following best explains this observation?
    (a)In viral genomes, the base pairing does not follow the
    standard Watson and Crick rules and allow G-A and C-T
    base pairs
    (b)Viral genomes are linear and tolerate base pair mismatches.


(c)Nucleic acids from viruses are rightly complexed with
nucleic acid binding proteins and so, cannot base pair
another
(d)The genome of bacteriophage φ× 174 is single-stranded


  1. Which one of the following does not follow the central
    dogma of molecular biology? [CBSE AIPMT 2010]
    (a) Pea (b) Mucor (c) Chlamydomonas (d) HIV

  2. hnRNA undergoes two additional processing. Out of
    which, in one of them an unusual nucleotide (methyl
    guanosine triphosphate) is added to the 5 ′ end of
    hnRNA. This is known as [AIIMS 2009]
    (a) capping (b) tailing (c) splicing (d) termination

  3. Whose experiments cracked the DNA and discovered
    unequivocally that genetic code is triplet?
    [CBSE AIPMT 2009]
    (a) Nirenberg and Matthaei (b) Hershey and Chase
    (c) Morgan and Chase (d) Beadle and Tatum

  4. The length of DNA molecule greatly exceeds the
    dimensions of the nucleus in eukaryotic cells. How is
    this DNA accommodated? [CBSE AIPMT]
    (a) Deletion of non-essential genes
    (b) Super coiling in nucleosomes
    (c) DNAase digestion
    (d) Through elimination of repetitive DNA
    10 .Automated DNA sequencers, work on the principle of
    the method developed by
    (a) Erwin Chargaff (b) Maurice Wilkins
    (c) Frederick Sanger (d) Alec Jeffreys
    11 .During transcription RNA polymerase holoenzyme
    binds to a gene promoter and assumes a saddle-like
    structure. What is its DNA-binding sequence?
    (a) TTAA (b) AATT (c) CACC (d) TATA
    12 .The haploid content of human DNA is
    (a) 3 3. × 106 bp (b) 3 3. × 109 bp
    (c) 4 6. × 106 bp (d) 6 6. × 109 bp
    13 .Alec Jeffreys developed the DNA fingerprinting
    technique. The probe he used was
    (a) ribozyme (b) sex chromosomes
    (c) SNP (d) VNTR


MASTER


Answers
1.(c) 2.(c) 3.(d) 4.(a) 5.(a) 6.(d) 7.(c) 8.(d) 9.(a) 10.(c)
11.(d) 12.(b) 13.(c) 14.(a) 15.(c) 16.(b) 17.(c) 18.(c) 19.(b) 20.(d)
21.(c) 22.(c) 23.(a) 24.(a) 25.(d) 26.(a) 27.(b) 28.(c) 29.(d) 30.(d)
31.(c) 32.(c) 33.(b) 34.(c) 35.(b) 36.(a) 37.(b) 38.(a) 39.(d) 40.(b)
41.(d) 42.(d) 43.(d) 44.(c) 45.(a) 46.(b) 47.(a) 48.(b) 49.(c) 50.(b)
51.(a) 52.(c) 53.(b) 54.(c) 55.(c) 56.(c) 57.(d)

Answers
1.(a) 2.(c) 3.(c) 4.(c) 5.(d) 6.(d) 7.(a) 8.(a) 9.(b) 10.(c)
11.(d) 12.(b) 13.(d)
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