Personalized_Medicine_A_New_Medical_and_Social_Challenge

Table 1 Projections for technological, medical, and integrational consideration for implementa-
tion of personalized medicine (modified from ESF Forward Look 2012 )

Projections

for 5 years 10 years 20 years

Technology Linear technologies Building interaction

networks

Measuring dynamic

networksin vivo

Genomics,

trancriptomics,

metabolomics, etc.

Molecular interactions Real-time monitoring

Environmental

monitoring

Gene–environment

interactions

Remote sensing

Human resources Alerting mechanisms

Responsive user

interfaces

Medicine Proof of principle Introduction Implementation and

refinement

Target available technol-

ogy on one disease area

Cumulative data to follow

the person

Integration of imaging

technology in physio-

logical monitoring

Identify available

resources (electronic

health records, cohorts,

etc.)

Dynamic qualitative/quan-

titative measures

In silicomodel for

individual patients

Enhance biobanks and

clinical sampling

Synergistic outputs from

multiple markers

Real-time monitoring

(nanomaterials)

Expand measures for

healthy individuals

ICT infrastructure to sup-

port real-time health care

delivery across regions

Remote monitoring/

personalized

telemedicine

Noninvasive information

collection and sharing

Increased precision of

imaging technologies and

therapy

Integration Discovery Validation Implementation

Core, -omics

technologies

Definition of purpose Nanotechnology

Epigenetics Achievabe targets Longitudinal data

Prototype model Testing of infrastructure Systematic data

collection

Enforcemet of

standards

Data sharing

E-learning

Personalized Medicine: The Path to New Medicine 15