Personalized_Medicine_A_New_Medical_and_Social_Challenge

(Barré) #1

  • genomic medicine—individual genome sequence-based prediction—far too
    narrow, Simmons, Dinan, Robinson et al. ( 2012 );^23

  • stratified medicine—identification of subgroups of patients with a particular
    disease who respond to a particular treatment or are at risk of side effects in
    response to such treatment—concept also applicable torisk stratification for
    prevention (thus, stratification is an important step towards “public”
    personalised medicine), Trusheim et al. ( 2007 );^24

  • precision medicine—targeting of the particular elements responsible for partic-
    ular pathology in a particular individual at a particular point in time (genomic
    and biological factors + stratification + environmental and lifestyle influences)—
    closest to the concept of “public” personalised medicine and often used as an
    alternative term, Mirnezami et al. ( 2012 ),^25 National Research Council Com-
    mittee on a Framework for Developing a New Taxonomy of Disease ( 2012 ),^26
    Cesuroglu et al. ( 2012 ).^27


4.2 Medical Data


The main “tool” of personalised medicine is(personal) medical information.
Therefore, a great challenge is in front of the entire health care system to create a
formal legal framework for ethically correct data handling.
The attention that is given to medical data and its handling highlights the very
essence of personalised medicine. Namely, the redefinition of the position of every
citizen as a potential user of the health care system recognises him/her as both the


“ME”
MEDICINE

“WE”
MEDICINE

“PUBLIC”
PERSONALISED MEDICINE

Fig. 1“Public”
personalised medicine as a
bridge towards “we”
medicine


(^23) See Simmons et al. ( 2012 ), pp. 85–91.
(^24) See Trusheim et al. ( 2007 ), pp. 287–293.
(^25) See Mirnezami et al. ( 2012 ), pp. 489–491.
(^26) See National Research Council Committee on a Framework for Developing a New Taxonomy of
Disease ( 2012 ).
(^27) See Cesuroglu et al. ( 2012 ), pp. 115–119.
86 V. Mic ́ovic ́et al.

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