Treatment of Inflammatory Bowel Disease with Biologics

195 was thought to be implicated in 32% of the cases. Anti-TNF therapy was re-initiated in 27 patients approximately 11.2 months ...

196 was 21 ± 18 days (n = 40), and patients had an average of 2.1 ± 1.3 infusions (n = 76) prior to symptom development. The mor ...

197 Clostridium difficile CDI has become an epidemiologic phenomenon as a leading cause of hospital- associated gastrointestinal ...

198 Viral Infections Influenza Immunosuppressed patients may be at increased risk for developing complications related to influe ...

199 or anti-HBs) > 100 international units/liter (IU/L) should ideally be maintained dur- ing biologic therapy to achieve ade ...

200 Hepatitis C Virus The prevalence of hepatitis C virus (HCV) among patients with IBD appears similar to the general populatio ...

201 Epstein-Barr Virus Reactivation of Epstein-Barr virus (EBV) has been reported to be more frequent among IBD patients compare ...

202 Herpes Simplex Virus Immunosuppressed patients may experience more severe, frequent, and extensive manifestations of primary ...

203 Marks DJB, Harbord MWN, MacAllister R, Rahman FZ, Young J, Al-Lazikani B, et  al. Defective acute inflammation in Crohn’s d ...

204 Kay J, Fleischmann R, Keystone E, Hsia EC, Hsu B, Mack M, et al. Golimumab 3-year safety update: an analysis of pooled data ...

205 MacDonald J, McDonald J.  Natalizumab for induction of remission in Crohn’s disease. Cochrane Database Syst Rev. 2007;24:CD ...

206 Abitbol Y, Laharie D, Cosnes J, Allez M, Nancey S, Amiot A, et al. Negative screening does not rule out the risk of tubercu ...

207 Lee JH, Slifman NR, Gershon SK, Edwards ET, Schwieterman WD, Siegel JN, et al. Life- threatening histoplasmosis complicatin ...

208 Bowie VL, Snella KA, Gopalachar AS, Bharadwaj P.  Listeria meningitis associated with infliximab. Ann Pharmacother. 2004;38 ...

209 disease patients does not impact immune response or safety of vaccine. Gastroenterology. 2014;146:S-586. Rahier JF, Papay P ...

210 Pompili M, Biolato M, Miele L, Grieco A.  Tumor necrosis factor-α inhibitors and chronic hepatitis C: a comprehensive liter ...

211 Jansen L, Vos X, Löwenberg M. Herpes simplex induced necrotizing tonsillitis in an immu- nocompromised patient with ulcerat ...

© Springer International Publishing AG 2018 213 A.S. Cheifetz, J.D. Feuerstein (eds.), Treatment of Inflammatory Bowel Disease w ...

214 mented in the literature. This is likely due to the lower frequency and more insidious development over time of malignant co ...

215 5 4.5 4 3.5 2.5 3 SIR 2 1 0 1978–1987 1988–1997 1998–2009 1.5 0.5 Intestinal Any Cancer Hematological 5 4.5 4 3.5 2.5 3 SIR ...