148
Molander et al. [^67
]
CD,17; UC, 30
Prospective observational (83% with concomitant IMM)
CD: 29% (1.1 year)
Nil identified
Age, gender, duration of disease, location, disease activity at discontinuation
100% (CD)
IBDU: 5
UC: 35% (1.1 year)
90% (UC)
Armuzzi et al. [^55
]
CD: 65
Retrospective (% of with concomitant IMM not reported)Retrospective (71% with concomitant IMM)
CD: 49% [median 1.1(0.3–6.2) years]
Absence of mucosal healing
Not reported
UC: 31
UC: 41% [median 1.3(0.3–2.5) years]
High CRP
Casanova et al. [^60
]
CD: 717UC: 338
24% (1 year)
Adalimumab (rather than infliximab)
Not available
75%
38% (2 years)46% (3 years)
Elective discontinuation of anti-TNF-
α therapy
56% (5 years)
Discontinuation of anti-TNF-
α due to adverse
eventsYounger age at discontinuationNo maintenance IMM
Authors
Number of participants (
n)
Study design
Relapse rate
Significant predictors of relapse
Predictors evaluated but not found to be significant
Recapture rate
Table 10.1
(continued)
H.H. Shim and C.H. Seow