Treatment of Inflammatory Bowel Disease with Biologics

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  1. Lobaton T, et al. Efficacy and safety of anti-TNF therapy in elderly patients with inflammatory
    bowel disease. Aliment Pharmacol Ther. 2015;42(4):441–51.

  2. Desai A, et al. Older age is associated with higher rate of discontinuation of anti-TNF therapy
    in patients with inflammatory bowel disease. Inflamm Bowel Dis. 2013;19(2):309–15.

  3. Ha C, Katz S. Management of inflammatory bowel disease in the elderly: do biologicals offer
    a better alternative? Drugs Aging. 2013;30(11):871–6.

  4. Katz S, Surawicz C, Pardi DS. Management of the elderly patients with inflammatory bowel
    disease: practical considerations. Inflamm Bowel Dis. 2013;19(10):2257–72.

  5. Kennedy NA, et al. Relapse after withdrawal from anti-TNF therapy for inflammatory bowel
    disease: an observational study, plus systematic review and meta-analysis. Aliment Pharmacol
    Ther. 2016;43(8):910–23.

  6. Gisbert JP, Marin AC, Chaparro M.  The risk of relapse after anti-TNF discontinuation in
    inflammatory bowel disease: systematic review and meta-analysis. Am J Gastroenterol. 2016;
    111(5):632–47.

  7. Papamichael K, Vermeire S.  Withdrawal of anti-tumour necrosis factor alpha therapy in
    inflammatory bowel disease. World J Gastroenterol. 2015;21(16):4773–8.

  8. de Suray N, et  al. Close monitoring of CRP and fecal calprotectin is able to predict clini-
    cal relapse in patients with Crohn’s disease in remission after infliximab withdrawal. A sub-
    analysis of the Stori study. Gastroenterology. 2012;142(5):S149.

  9. Vermeire S, Van Assche G, Rutgeerts P. Laboratory markers in IBD: useful, magic, or unneces-
    sary toys? Gut. 2006;55(3):426–31.

  10. Melmed GY, Targan SR.  Future biologic targets for IBD: potentials and pitfalls. Nat Rev.
    Gastroenterol Hepatol. 2010;7(2):110–7.


L. Zhu and G.Y. Melmed
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