Bugliani M, including a total of 13 samples, 7 samples from
non-T2DM and 6 samples from T2DM [23]. Also, this microarray
dataset is compliant with the Minimum Information About a
Microarray Experiment (MIAME) guideline [24]. Its microarray
platform is Affymetrix Human Genome U133A Array.
R is downloaded from https://cran.r-project.org/bin/
windows/base. RStudio is downloaded from https://www.
rstudio.com/products/rstudio/download. Cytoscape [25]is
downloaded fromhttp://www.cytoscape.org.
The R packages,affy[26],RColorBrewer[27], simpleaffy[28],
limma[29], hgu133a.db[30],andpsych[31], should be installed
(Fig.1).
Fig. 1Installation of R packages
Building Biological Networks from Gene Expression Data 181