4 Dynamics of DNA Supercoiling 59(a)
(b)
Fig. 4.9.DNA-topoisomerase interface calculated using advanced Voronoi tessel-
lation. (a) Distribution of voids on the DNA-enzyme interface calculated using ad-
vanced Voronoi procedure as implemented in TOPOS [31] program package. Voids
are drawn as semi-transparent polyhedra, DNA isyellow;(b) Dense DNA-protein
contacts are shown asred balls. All DNA atoms in contact with protein are phosphate
oxygen