172 Chapter 11
Description/action
May be used for
Contraindications and precautions
Monoamine oxidase B
inhibitors (MAOBIs), Selegiline
Inhibits the actions of the enzyme
monoamine oxidase B which catabolizes (breaks down) catecholamines, including dopamine, adrenaline and serotonin in the CNS
May be prescribed in cases of
cognitive dysfunction in older cats (Gunn-Moore, 2011)
Should never be used in combination
with TCAs, SSRIs or other medications including tramadol, metronidazole, prednisolone or trimethoprim
Megestrol acetate
A powerful progestogen (hormone)
that can delay or prevent oestrus in entire female cats
Has been used to treat urine
spraying; however, the damaging side-effects outweigh the potential benefits
Common serious side-effects of
weight-gain, mammary hyperplasia/neoplasia, blood dyscrasia (abnormal blood pathology) and increased risk of diabetes
(Crowell-Davies and Landsberg, 2009; Gunn-Moore, 2011; DePorter
et al
., 2016.)
Table 11.1.
Continued.