Advice for Veterinary Professionals 175
Table 11.2.
Examples of nutraceuticals* and herbal supplements that may aid behaviour therapy. (Adapted from DePorter
et al
., 2016.)
Supplement
How does it work
Indications
Precautions
Alpha CasozepineA nutraceutical derived from
casein, a protein in cow’s milk
Reported to have anxiolytic effects
similar to benzodiazepines
Fear, anxiety, stress
None reported
TryptophanAn essential amino acid (one of
the building blocks of proteins) and the dietary precursor of serotonin
May increase available levels of
serotonin or enhance its transmission
Anxiety, stress
May increase the risk of
serotonin syndrome
‡ if used
concurrently with drugs that increase serotonin levels
TheanineAn amino acid found in green
tea that has a chemical structure similar to glutamate
May block the effects of glutamate and
increase GABA. An advantage is that it is highly palatable to cats
Fear, anxiety, stress
None reported
Docosahexanoic acid (DHA)
and Eicosapentaenoic acid (EPA)
Polyunsaturated fatty acids
Essential for early brain and retinal
development, and to help maintain brain function in adults
For healthy brain and
retinal development in kittens and to improve cognitive function in senior cats
Avoid high doses, which may
result in gastrointestinal effects, weight gain, altered immune function and poor wound healing (Lennox, 1993)
ValerianHerbValeriana officinalis
Usually prepared with other herbs
in either a tablet or liquid form for oral administration or in a spray or diffuser for environmental use. Can have sedative properties
Anxiety, fear, stress,
excitability, timidity, and car sickness
CatnipHerbNepeta cataria
The active ingredient is the essential oil
nepetalactone which affects the CNS via the olfactory bulb
Does not affect all cats (only around
50-70%) and effects can be variable with affected cats showing a wide range of behaviours
Encouragement to play
and aid enrichment. May be used to encourage scratching on a suitable surface
May cause increased
arousal resulting in short term aggression. Catnip intoxication has been reported
*A nutraceutical is a food or food derivative that is said to have medicinal or health-giving properties.‡Serotonin syndrome is a term used to describe a potentially fatal condition that can arise if serotonin levels or availability are excessively increased.