Biomechanics of the Cruciate Ligaments 19stability compared to experimental dogs, as sti-
fle inflammation will promote graft resorption.
Conclusions
The biomechanical properties of the cruciate lig-
aments are essential for stifle joint stabilization.
It is the degradation of these properties that
ultimately leads to cruciate ligament rupture
and loss of joint stability. Further under-
standing of the relationship between synovitis,
ligament degradation and ligament biomechan-
ical properties is needed, as is development of
disease-modifying treatments to combat the
inflammatory joint environment associated
with cruciate ligament rupture in the dog.
Although progress has been made, the contin-
ued lack of understanding regarding the mech-
anisms involved in the development of cruciate
ligament rupture in affected dogs, particularly
with regard to synovitis, remains a barrier to
the development of better surgical treatments.
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