Vaccination of Domestic and Wild Animals Against Tuberculosis 223
Rizzi, C., Bianco, M.V., Blanco, F.C., Soria, M., Gravisaco, M.J., et al. (2012) Vaccination with a BCG
strain overexpressing Ag85B protects cattle against Mycobacterium bovis challenge. PLoS ONE 7,
e51396.
Roy, A., Risalde, M.A., Casal, C., Romero, B., de Juan, L., et al. (2017) Oral vaccination with heat- inactivated
Mycobacterium bovis does not interfere with the antemortem diagnostic techniques for tuberculosis in
goats. Frontiers in Veterinary Science 4, 124.
Santos, N., Almeida, V., Gortázar, C. and Correia-Neves, M. (2015a) Patterns of Mycobacterium tuberculo-
sis complex excretion and characterization of super-shedders in naturally-infected wild boar and red
deer. Veterinary Research 46, article 129, DOI: 10.1186/s13567-015-0270-4.
Santos, N., Santos, C., Valente, T., Gortázar, C., Almeida, V., et al. (2015b) Widespread environmental
contamination with Mycobacterium tuberculosis complex revealed by a molecular detection protocol.
PLoS ONE 10, e0142079.
Sidders, B., Pirson, C., Hogarth, P.J., Hewinson, R.G., Stoker, N.G., et al. (2008) Screening of highly
expressed mycobacterial genes identifies Rv3615c as a useful differential diagnostic antigen for
Mycobacterium tuberculosis complex. Infection and Immunity 76, 3932–3939.
Skinner, M.A., Wedlock, D.N. and Buddle, B.M. (2001) Vaccination of animals against Mycobacterium
bovis. Revue Scientifique et Technique (International Office of Epizootics) 20, 112–132.
Skinner, M.A., Buddle, B.M., Wedlock, D.N., Keen, D., de Lisle, G.W., et al. (2003) A DNA prime-
Mycobacterium bovis BCG boost vaccination strategy for cattle induces protection against bovine
tuberculosis. Infection and Immunity 71, 4901–4907.
Skinner, M.A., Wedlock, D.N., de Lisle, G.W., Cooke, M.M., Tascon, R.E., et al. (2005) The order of prime-
boost vaccination of neonatal calves with Mycobacterium bovis BCG and a DNA vaccine encoding
mycobacterial proteins Hsp65, Hsp70, and Apa is not critical for enhancing protection against bovine
tuberculosis. Infection and Immunity 73, 4441–4444.
Thom, M.L., McAulay, M., Vordermeier, H.M., Clifford, D., Hewinson, R.G., et al. (2012) Duration of immu-
nity against Mycobacterium bovis following neonatal vaccination with bacillus Calmette–Guérin Dan-
ish: significant protection against infection at 12, but not 24 months. Clinical and Vaccine Immunology
19, 1254–1260.
Thomas, J., Risalde, M.Á., Serrano, M., Sevilla, I., Geijo, M., et al. (2017) The response of red deer to oral
administration of heat-inactivated Mycobacterium bovis and challenge with a field strain. Veterinary
Microbiology 208, 195–202.
Tompkins, D.M., Ramsey, D.S.L., Cross, M.L., Aldwell, F.E., de Lisle, G.W., et al. (2009) Oral vaccination
reduces the incidence of bovine tuberculosis in a free-living wildlife species. Proceedings of the Royal
Society B: Biological Sciences 276, 2987–2995.
Tompkins, D.M., Buddle, B.M., Whitford, J., Cross, M.L., Yates, G.F., et al. (2013) Sustained protection
against tuberculosis conferred to a wildlife host by a single dose vaccination. Vaccine 31, 893–899.
van der Heijden, E.M.D.L., Chileshe, J., Vernooij, J.C.M., Gortazar, C., Juste, R.A., et al. (2017) Immune
response profiles of calves following vaccination with live BCG and inactivated Mycobacterium bovis
vaccine candidates. PLoS One 12(11), e0188448.
Vordermeier, H.M., Whelan, A., Cockle, P.J., Farrant, L., Palmer, N., et al. (2001) Use of synthetic peptides
derived from the antigens ESAT-6 and CFP-10 for differential diagnosis of bovine tuberculosis in
cattle. Clinical and Diagnostic Laboratory Immunology 8, 571–578.
Vordermeier, H.M., Chambers, M.A., Cockle, P.J., Whelan, A.O., Simmons, J., et al. (2002) Correlation of
ESAT-6-specific gamma interferon production with pathology in cattle following Mycobacterium bovis
BCG vaccination against experimental bovine tuberculosis. Infection and Immunity 70, 3026–3032.
Vordermeier, H.M., Villarreal-Ramos, B., Cockle, P.J., McAulay, M., Rhodes, S.G., et al. (2009) Viral booster
vaccines improve Mycobacterium bovis BCG-induced protection against bovine tuberculosis. Infec-
tion and Immunity 77, 3364–3373.
Waters, W.R., Palmer, M.V., Nonnecke, B.J., Thacker, T.C., Scherer, C.F.C., et al. (2007) Failure of a Myco-
bacterium tuberculosis DRD1 DpanCD double deletion mutant in a neonatal calf aerosol M. bovis
challenge model: comparisons to responses elicited by M. bovis bacille Calmette–Guérin. Vaccine
25, 7832–7840.
Waters, W.R., Palmer, M.V., Nonnecke, B.J., Thacker, T.C., Scherer, C.F.C., et al. (2009) Efficacy and immu-
nogenicity of Mycobacterium bovis DRD1 against aerosol M. bovis infection in neonatal calves. Vac-
cine 27, 1201–1209.
Waters, W.R., Palmer, M.V., Buddle, B.M. and Vordermeier, H.M. (2012) Bovine tuberculosis vaccine
research: historical perspectives and recent advances. Vaccine 30, 2611–2622.