Index 263
raw 20–21, 240
UK 20
meerkats, Mycobacterium suricattae in 106
meningitis 22, 24
metabolites 196
Mexico 208
human tuberculosis 33
zoonotic tuberculosis 21
mice 129, 155, 159
Bordetella pertussis in 162
granulomas 129, 129
lesions 129
lungs 162
Mycobacterium tuberculosis in 146
Salmonella enterica in 162
micro-epidemics 65, 68–69
micro-RNA (miRNA) 182, 194, 211
circulating 197
microarray technology 177
microbacterial antigens 210
microscopy, sputum smear 16, 248
milk 16, 24, 31, 33, 47, 80, 239, 241, 250
camels 85, 86
Ethiopia 20
goats 81
heat treatment 20
pasteurisation 17, 19, 20, 22, 33, 35, 36, 226,
239, 240, 242–243
raw 20, 22, 238, 242
temperature 20
testing 241
unpasteurised 22, 34, 37, 240
mitochondria 145
molecular epidemiology 17, 59–60, 65, 67, 70
molecular genetic tests 61
molecular patterns, damage-associated (DAMs) 140,
144
molecular surveillance 59–60
molecular typing 60, 61, 66
Africa 64
Northern Ireland 68
molecular virulence mechanisms 106–121
moose 96
Morocco 37
cattle–human transmission 37, 37
stakeholders 38
mortality, Mycobacterium bovis 19
MPB70 proteins 112
mRNA 182, 200
mucosal invariant T cells (MAIT) 154, 160
multi-host complexes 97–99
multi-locus VNTR analysis (MLVA) 61, 62, 63, 64,
65, 66, 67, 69
multi-nucleated giant cells (MNGCs) 124, 125, 126,
128, 133
multi-species transmission 101
multidrug-resistant tuberculosis 24
multiplicity of infection (MOI) 145
muscle, Mycobacterium bovis 21
Mustelidae 132, 217
mycobacteria 70, 143, 144, 198
cell envelope 109–111, 113
control 144–145
ecology 61
environmental sources 46
evolution 107, 193
genomes 61
in vitro 111
molecular surveillance systems 68
pathogenic 127
proteins 115
secretory systems 111–112
twin arginine transporter (Tat) 112
virulence 108, 109, 110–111
virulent strains 147
mycobacterial interspersed repetitive units
(MIRUs) 61
mycobacterial vaccines, live attenuated 208–209
Mycobacterium
caprae 67, 81, 84, 114, 122
in goats 81, 106, 207, 211, 212
kansasii 176
microti 82, 84, 106
orygis 106, 114
pinnipedii 106
smegmatis 145
suricattae 106
Mycobacterium avium 157, 162, 175, 176, 177, 192,
211, 250
hominissuis 65
Mycobacterium avium complex (MAC) 82
Mycobacterium bovis
Argentina 65
in Asian water buffalo 84
in badgers 93–94, 99–100
beta-interferon 147
Brazil 65
Burundi 64
in calves 155
in camelids 84, 131
in cattle 43–57, 63
in children 22
clinical challenges 23–24
in companion animals 130
in deer 96–97, 98
in domestic pigs 82–84
dynamics and persistence 97–99
early generalisation 123
epidemiology 43–57
Ethiopia 64
evolution 107
in feral pigs 95–96
foodborne 12
genomes 69